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Phenazone

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Identification
Molecular formula
C20H20N2O2
CAS number
60-80-0
IUPAC name
4-[3-(4-aminophenyl)-3-oxo-propyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

At room temperature, Phenazone is a solid, typically existing in a finely divided crystalline form. It is stable under normal conditions and does not readily decompose or volatilize.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.00
Boiling point (Celsius)
349.60
Boiling point (Kelvin)
622.80
General information
Molecular weight
284.34g/mol
Molar mass
284.3380g/mol
Density
1.1090g/cm3
Appearence

Phenazone is typically a white or slightly yellowish crystalline powder with no distinct odor. The compound can form elongated, needle-like crystals when precipitated from solution.

Comment on solubility

Solubility of 4-[3-(4-aminophenyl)-3-oxo-propyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one

The solubility of 4-[3-(4-aminophenyl)-3-oxo-propyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one can be influenced by various factors including its chemical structure and intermolecular interactions. Here are a few key points to consider:

  • Polar vs Non-Polar: Compounds containing polar functional groups tend to be more soluble in polar solvents, while non-polar compounds prefer non-polar solvents. Understanding the balance of these characteristics is crucial.
  • Hydrogen Bonding: This compound may engage in hydrogen bonding due to the presence of amino groups, which can enhance its solubility in aqueous solutions.
  • Temperature Influence: Typically, an increase in temperature can result in increased solubility for many solid compounds.
  • pH Dependence: The solubility may change with pH, particularly if the compound has acidic or basic groups that can ionize under different pH conditions.

In conclusion, the solubility behavior of 4-[3-(4-aminophenyl)-3-oxo-propyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one illustrates an intricate interplay of its molecular characteristics and the surrounding environment. As the renowned chemist Linus Pauling once said, "The properties of a substance are determined by the kind of bonding that occurs between its atoms and of the nature of these atoms themselves." Understanding this compound's solubility requires a thoughtful examination of its structure and the solvents being utilized.

Interesting facts

Interesting Facts about 4-[3-(4-Aminophenyl)-3-oxo-propyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one

This fascinating compound belongs to the class of pyrazolone derivatives, which are known for their diverse pharmacological properties. The intricate structure of this compound hints at its potential applications in various fields, particularly in medicinal chemistry.

Key Features:

  • Pharmacological Significance: Compounds like this one have been investigated for their anti-inflammatory and analgesic properties. This makes them valuable in the development of new pain-relief medications.
  • Structure-Activity Relationship: The presence of the 4-aminophenyl moiety enhances the biological activity of the molecule, showcasing how subtle changes in chemical structure can lead to significant variations in function.
  • Multifunctionality: The pyrazolone framework in this compound allows for modifications that can tailor its pharmacological effects, making it a versatile building block in drug design.
  • Research Applications: Ongoing studies into similar compounds are revealing their potential for use in treating chronic diseases, demonstrating the importance of continued research into novel chemical entities.

As scientists explore the potential of 4-[3-(4-aminophenyl)-3-oxo-propyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one, they pursue not only the optimization of its therapeutic effects but also a deeper understanding of its mechanism of action. The journey of developing such compounds underlines the complex interplay between chemistry and biology, making each discovery a step toward improved healthcare solutions.

In summary, this compound is a prime example of how intricate molecular designs can lead to valuable medicinal applications, showcasing the creativity and innovation prevalent in the field of chemistry.

Synonyms
BRN 0932002
4-(2-(p-Aminobenzoyl)ethyl)antipyrine
ANTIPYRINE, 4-(2-(p-AMINOBENZOYL)ETHYL)-
24428-98-6
1-Phenyl-2,3-dimethyl-4-(beta-(p-aminobenzoyl)ethyl)pyrazol-5-one
DTXSID80179187