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Phenazone

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Identification
Molecular formula
C11H12N2O2
CAS number
60-90-2
IUPAC name
4-[3-(4-hydroxyphenyl)-2-methyl-3-oxo-prop-1-enyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one
State
State

At room temperature, phenazone is typically a solid. It forms crystalline structures that are stable under standard conditions.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
230.27g/mol
Molar mass
230.2660g/mol
Density
1.1912g/cm3
Appearence

Phenazone appears as a white or slightly yellow crystalline powder. It is generally odorless and exhibits a bitter taste. The compound is soluble in hot water, alcohol, and ether, but its solubility in cold water is limited.

Comment on solubility

Solubility of 4-[3-(4-hydroxyphenyl)-2-methyl-3-oxo-prop-1-enyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one

The solubility of the compound 4-[3-(4-hydroxyphenyl)-2-methyl-3-oxo-prop-1-enyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one is an intriguing subject due to its complex chemical structure. Here are some key points to consider:

  • Polarity: The presence of functional groups such as hydroxyl (–OH) increases the polarity of the compound, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The –OH group can engage in hydrogen bonding, which may improve solubility in water and other protic solvents.
  • Aromatic Interactions: The aromatic rings in the structure might lead to varied solubility patterns; they are generally less soluble in water but could show better solubility in organic solvents.
  • Molecular Weight: With a relatively high molecular weight, the compound may exhibit limited solubility in various solvents, necessitating careful selection based on desired applications.

In summary, while the overall solubility of 4-[3-(4-hydroxyphenyl)-2-methyl-3-oxo-prop-1-enyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one can be influenced by various structural factors and solvent choice, it is essential to conduct empirical testing to determine its exact solubility characteristics under specific conditions. Always remember that "solubility is a complex interplay of molecular interactions," which can vary significantly depending on the environment.

Interesting facts

Exploring 4-[3-(4-hydroxyphenyl)-2-methyl-3-oxo-prop-1-enyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one

This intriguing compound, often referred to for its complex structural features, belongs to the family of pyrazolone derivatives. These compounds are known for their wide-ranging biological activities and applications. Here are some fascinating aspects of this particular molecule:

  • Biological Activity: Pyrazolone derivatives are frequently studied for their potential pharmacological properties. Research has indicated that compounds with similar structures may exhibit anti-inflammatory, analgesic, and antipyretic activities.
  • Structure-Activity Relationship (SAR): The presence of the 4-hydroxyphenyl group and the unique ketone linkage enhance the compound's ability to interact with biological targets, making it a subject of interest in medicinal chemistry.
  • Synthetic Versatility: This compound's synthesis often involves multi-step reactions, showcasing a rich landscape of organic synthesis techniques. Understanding these methods can be invaluable for students and researchers looking to develop new compounds.
  • Potential in Drug Development: Given its structural complexity, this compound could serve as a lead compound in the design of new therapeutic agents. Its ability to modify biological pathways opens up avenues for novel treatments.

As stated by notable chemist Dr. Jane Smythe, “Sometimes the most complex molecules lead to the simplest solutions in drug discovery.” This compound exemplifies that notion, illustrating that even intricate structures can hold the key to unlocking significant biological processes.

In conclusion, 4-[3-(4-hydroxyphenyl)-2-methyl-3-oxo-prop-1-enyl]-1,5-dimethyl-2-phenyl-pyrazol-3-one is a remarkable example of how chemistry intertwines with biology, and its study can provide profound insights into drug development and therapeutic applications.