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Bupropion

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Identification
Molecular formula
C13H18ClNO2
CAS number
34911-55-2
IUPAC name
4-(3-azabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one
State
State

At room temperature, bupropion is typically found in a solid state.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.15
Boiling point (Celsius)
308.40
Boiling point (Kelvin)
581.55
General information
Molecular weight
239.75g/mol
Molar mass
239.7470g/mol
Density
1.2570g/cm3
Appearence

Bupropion is generally available as a crystalline solid and appears as a white powder. It is often used in tablet form as a medication.

Comment on solubility

Solubility of 4-(3-azabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one

The solubility of 4-(3-azabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one can be influenced by several factors, making it a compound of interest in various chemical applications. Understanding its solubility characteristics is essential for its practical use and efficacy. Here are some key points to consider:

  • Polarity: The presence of polar functional groups in the compound can significantly enhance its solubility in polar solvents like water.
  • Solvent Interactions: Solubility may vary in different solvents due to the specific interactions (such as hydrogen bonding or Van der Waals forces) that can occur.
  • Temperature Effects: As with many organic compounds, increasing the temperature may facilitate better solubility by allowing more kinetic energy to overcome solvation barriers.
  • pH Influence: The solubility behavior could be altered under different pH conditions, especially if the compound contains acidic or basic moieties.
  • Stability in Solution: Chemical stability in various solvents can influence solubility and dissolution rates.
  • Concentration and Saturation: At certain concentrations, this compound may reach saturation, beyond which no additional solute can dissolve.

In conclusion, the solubility of 4-(3-azabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one is governed by its molecular interactions and the surrounding environment. Understanding its solubility profile is pivotal for applications in pharmaceuticals and material sciences.

Interesting facts

Interesting Facts about 4-(3-azabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one

This compound is a fascinating example of a synthetic organic molecule that showcases various properties and potential applications in science and medicine. Here are some remarkable aspects:

  • Structural Complexity: The inclusion of a bicyclic structure makes this compound intriguing to study. The azabicyclo[3.2.0]heptane moiety is known for its rigidity and unique three-dimensional shape, which can influence the compound's activity and interactions with biological targets.
  • Fluorine Substitution: The presence of a fluorine atom in the aromatic ring alters the electronic characteristics of the compound, potentially enhancing its binding affinity in biological systems. Fluorinated compounds often exhibit improved metabolic stability and bioavailability, making them valuable in drug design.
  • Potential Pharmacological Activity: Given the structural elements of this molecule, it is a candidate for investigation in areas such as neuropharmacology. Compounds featuring bicyclic amines are often explored for their properties as neurotransmitter reuptake inhibitors or in the development of analgesics.
  • Chemistry in Action: This compound can serve as a versatile building block in chemical synthesis. Its structural features might allow for various functionalization mechanisms, leading to derivatives with enhanced or modified properties.
  • Research Opportunities: There is ongoing interest in exploring the pharmacodynamics and pharmacokinetics of compounds like this one. Researchers might focus on how minor modifications to the structure can lead to significant changes in biological activity.

In summary, 4-(3-azabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one stands as an exciting platform for studying complex organic compounds and holds the potential for future therapeutic applications.