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FUB-144

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Identification
Molecular formula
C20H27ClFN2O
CAS number
2181072-50-2
IUPAC name
4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one;hydrochloride
State
State

At room temperature, FUB-144 hydrochloride is a solid.

Melting point (Celsius)
295.00
Melting point (Kelvin)
568.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
0.00g/mol
Molar mass
452.9510g/mol
Density
1.2000g/cm3
Appearence

FUB-144 hydrochloride appears as a white crystalline powder.

Comment on solubility

Solubility of 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one; hydrochloride

The solubility of the compound 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one; hydrochloride (C20H27ClFN2O) can be influenced by several key factors:

  • Polarity: The presence of the hydrochloride form typically increases solubility in water due to the ionic nature of the salt.
  • Temperature: Generally, increasing temperature can enhance solubility for many compounds. Therefore, it is prudent to conduct experiments at various temperatures to ascertain the precise solubility.
  • Solvent type: The choice of solvent significantly affects solubility; for organic compounds, using polar solvents like methanol or ethanol might lead to higher solubility than non-polar solvents.

In summary, while the hydrochloride salt form suggests good solubility in aqueous solutions, it is essential to consider these factors for specific solubility data. As with many compounds, "one size does not fit all," and empirical testing is often required to determine the exact solubility characteristics under various conditions.

Interesting facts

Interesting Facts about 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one; hydrochloride

This compound belongs to a specialized class of organic molecules known as spirocyclic compounds, which are characterized by their unique structure containing multiple rings that share a single atom. The specific spirocyclic nature of this compound gives it interesting properties that are of interest to both chemists and pharmacologists.

Key Features

  • Bioactivity: Compounds like this are often explored for their potential pharmacological activities. The incorporation of a fluorophenyl group can influence the compound's biological profile, enhancing its binding interactions with various biological targets.
  • Spiracyclic Structure: The azaspiro element indicates the presence of a nitrogen atom in the spirocyclic framework, which can significantly affect the compound's reactivity and stability. Such structures have been connected to a variety of biological activities, including antipsychotic and antidepressant effects.
  • Research Potential: Many compounds of this type are under investigation for their application in treating neurological and psychiatric disorders. This highlights the ongoing search for innovative treatments in mental health.

Significance in Chemistry

Moreover, the synthesis and characterization of spirocyclic compounds like this one are critical in the development of new medicinal agents. As chemists say, “The structure determines the function,” and the exploration of these unique frameworks can lead to the discovery of new mechanisms of action in drug design.

In summary, 4-(3-azaspiro[5.5]undecan-3-yl)-1-(4-fluorophenyl)butan-1-one; hydrochloride represents a fascinating intersection of structure and function, offering potential pathways for advancements in pharmaceuticals due to its unique biochemical properties. As research continues in this area, scientists remain hopeful about the innovative applications that may arise from such compounds.

Synonyms
NSC 90825
64-60-8
BUTYROPHENONE, 4-(3-AZASPIRO(5.5)UNDEC-3-YL)-4'-FLUORO-, HYDROCHLORIDE
DTXSID20213978
4-(3-Azaspiro(5.5)undec-3-yl)-4'-fluoro-butyrophenone hydrochloride
3-((4-p-Fluorophenyl-4-hydroxy)butyl)-3-azaspiro(5.5)undecane hydrochloride
DTXCID50136469
NSC90825
NSC-90825