Skip to main content

Varenicline tartrate

ADVERTISEMENT
Identification
Molecular formula
C13H14FN2OCl
CAS number
249296-44-4
IUPAC name
4-(3-azoniabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride
State
State

At room temperature, it is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
176.50
Melting point (Kelvin)
449.70
Boiling point (Celsius)
371.50
Boiling point (Kelvin)
644.70
General information
Molecular weight
305.22g/mol
Molar mass
305.2210g/mol
Density
1.1097g/cm3
Appearence

The compound appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-(3-azoniabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride

The solubility of the compound 4-(3-azoniabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride can be considered quite intriguing. As a quaternary ammonium salt due to the presence of the azoniabicyclo moiety, its solubility properties can vary significantly depending on the solvent used.

Factors Affecting Solubility

Several factors play a crucial role in determining the solubility of this compound:

  • Ionic Nature: Being a chloride salt, it is likely highly soluble in polar solvents like water, due to ion-dipole interactions.
  • Hydrophobic Interactions: The presence of the 4-fluorophenyl and butanone groups may induce some hydrophobic character, potentially affecting solubility in non-polar solvents.
  • Temperature and pH: Changes in temperature and solvent pH can lead to variations in solubility, often increasing solubility with rising temperature.

Conclusion

In conclusion, while 4-(3-azoniabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride is likely to demonstrate good solubility in polar media, the extent may depend significantly on the interactions described above. It remains important to conduct solubility tests in various solvents to fully characterize its properties.

Interesting facts

Interesting Facts about 4-(3-Azoniabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one; Chloride

This fascinating compound belongs to a unique class of quaternary ammonium salts, which are known for their diverse applications in various fields, including pharmaceuticals and materials science. Here are some noteworthy points about this compound:

  • Structure and Stability: The inclusion of a bicyclic structure provides notable stability and specific geometric orientations, enabling unique interactions in biological environments.
  • Biological Significance: Bicyclic amines, like the one found in this compound, have been studied for their potential in medicinal chemistry, particularly as they can exhibit interesting pharmacological properties.
  • Reactivity: The presence of the fluorine atom in the phenyl ring enhances the electronic properties of the molecule, often leading to increased lipophilicity and potentially influencing its interaction with biological receptors.
  • Potential Applications: This compound could be useful in drug design, owing to its unique structural features that may allow for selective targeting of specific biological pathways.
  • Synthetic Routes: The synthesis of such compounds often involves advanced organic techniques, showcasing the intricacies of chemical transformations that chemists employ to build complex molecular architectures.

In conclusion, compounds like 4-(3-azoniabicyclo[3.2.0]heptan-1-yl)-1-(4-fluorophenyl)butan-1-one; chloride not only pose intriguing challenges in terms of synthesis and characterization but also open doors to innovative discoveries in chemical and biological sciences. As one researcher aptly puts it: "The beauty of chemistry lies in its ability to weave complexity into simplicity."

Synonyms
15997-79-2
BUTYROPHENONE, 4-(3-AZABICYCLO(3.2.0)HEPTYL)-4'-FLUORO-, HYDROCHLORIDE
4-(3-Azabicyclo(3.2.0)heptyl)-p-fluorobutyrophenone hydrochloride
4-(3-Azabicyclo(3.2.0)heptyl)- p-fluorobutyrophenone hydrochloride