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Varenicline tartrate

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Identification
Molecular formula
C13H18ClN2F
C10H15N
CAS number
319473-96-6
IUPAC name
4-(3-azoniabicyclo[3.2.2]nonan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride
State
State

At room temperature, this compound remains in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
645.00
Boiling point (Kelvin)
918.15
General information
Molecular weight
361.84g/mol
Molar mass
361.8390g/mol
Density
1.1764g/cm3
Appearence

This compound appears as a white crystalline powder. Its crystalline nature can often result in a shiny appearance in larger aggregates, and it is typically odorless.

Comment on solubility

Solubility of 4-(3-azoniabicyclo[3.2.2]nonan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride

The solubility of the compound 4-(3-azoniabicyclo[3.2.2]nonan-1-yl)-1-(4-fluorophenyl)butan-1-one;chloride is influenced by various factors, including its ionic nature and molecular structure. Being a quaternary ammonium salt due to the presence of the azonia group, it generally exhibits high solubility in polar solvents.

Key aspects of the solubility are:

  • Solvent Polarity: The compound is likely to be soluble in water and other polar solvents due to its ionic characteristics, which facilitate interaction with polar molecules.
  • Cationic Properties: As a cationic compound, it may exhibit a strong affinity for anionic species, further enhancing its solubility in saline solutions.
  • Temperature Dependence: Solubility can increase with temperature, making it easier to dissolve in warmer conditions.
  • Limited Solubility in Nonpolar Solvents: Conversely, it will have poor solubility in nonpolar solvents, such as hydrocarbons, due to the lack of complementary interactions.

In experimental contexts, testing solubility should consider these factors since chemists can often manipulate conditions to increase the solubility of such compounds, thereby enhancing their utility in various applications.

Interesting facts

Interesting Facts About 4-(3-Azoniabicyclo[3.2.2]nonan-1-yl)-1-(4-fluorophenyl)butan-1-one; Chloride

This compound is a fascinating example of a synthetic molecular structure that incorporates complex bicyclic systems with functional groups. Here are some key points that make this compound stand out:

  • Novel Structure: The presence of the azabicyclic ring enhances the compound’s potential for interesting properties, especially in pharmaceutical contexts.
  • Functionalization: The inclusion of a fluorophenyl group is significant, as fluorine affects the electronic properties of molecules, often enhancing their stability and bioactivity.
  • Potential Applications: Compounds like this one have potential applications in medicinal chemistry, particularly in the design of drugs that can modulate neurotransmitter systems, due to their structural similarities to various neurotransmitters.
  • Charge Characteristics: The azonia moiety introduces a positive charge, which can influence the solubility and permeability of the compound in biological systems, making it an interesting subject for further investigation.
  • Biological Implications: Research has indicated that such bicyclic structures may have roles in cognitive enhancement and other neurochemical pathways, which could be explored in future studies.

As noted by many researchers in the field, “The intersection of structure and functionality is the heart of drug design.” This compound exemplifies that philosophy, combining structural complexity with potential therapeutic benefits.

Overall, 4-(3-azoniabicyclo[3.2.2]nonan-1-yl)-1-(4-fluorophenyl)butan-1-one; chloride serves as a noteworthy subject for continued research, promising insights into both chemistry and pharmacology.

Synonyms
4-(3-Azabicyclo(3.2.2)nonyl)-4-fluorobutyrophenone hydrochloride
15997-77-0
BUTYROPHENONE, 4-(3-AZABICYCLO(3.2.2)NONYL)-4'-FLUORO-, HYDROCHLORIDE