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Phloxine B

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Identification
Molecular formula
C20H2Cl4Na2O5
CAS number
18472-87-2
IUPAC name
4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid;1-methyl-2-[2-(2-thienyl)vinyl]-5,6-dihydro-4H-pyrimidine
State
State
Phloxine B is typically found in solid form at room temperature, often as a crystalline powder or granules.
Melting point (Celsius)
265.00
Melting point (Kelvin)
538.00
Boiling point (Celsius)
349.00
Boiling point (Kelvin)
622.00
General information
Molecular weight
692.46g/mol
Molar mass
692.4560g/mol
Density
1.5200g/cm3
Appearence
Phloxine B appears as a pinkish to reddish powder with potential vibrant coloration when dissolved in water. It is commonly used as a dye in biological staining, imparting a characteristic red hue.
Comment on solubility

Solubility Overview

The solubility of 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid;1-methyl-2-[2-(2-thienyl)vinyl]-5,6-dihydro-4H-pyrimidine can be quite complex due to its multifaceted chemical structure. Understanding its solubility is essential for applications such as pharmaceutical formulations and synthesis processes.

Factors Influencing Solubility:

  • Polarity: The presence of multiple functional groups, including carboxylic acids and hydroxyl groups, generally enhances solubility in polar solvents.
  • Hydrogen Bonding: This compound can engage in extensive hydrogen bonding with solvents, promoting solubility in water and other polar media.
  • Hydrophobic Interactions: The naphthalene and thienyl components introduce hydrophobic characteristics that may limit solubility in purely polar environments.
  • pH Sensitivity: The ionization state of the carboxylic acid groups can be significantly influenced by the pH, affecting solubility across different environments.

As a result of these factors, the compound demonstrates:

  • Higher solubility in acidic solutions where carboxylic groups are protonated, reducing hydrophilicity.
  • Variable solubility in organic solvents depending on the balance of hydrophobic and hydrophilic elements.

In summary, predicting the solubility of this compound requires careful consideration of its intricate structure and the surrounding conditions. As a guiding principle, one might say, "A compound’s solubility is as dynamic as its structure." Understanding these nuances is crucial for harnessing the full potential of this compound in practical applications.

Interesting facts

4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 1-methyl-2-[2-(2-thienyl)vinyl]-5,6-dihydro-4H-pyrimidine

This compound is a fascinating example of a complex organic molecule that combines the structural features of naphthalene and pyrimidine. Here are some intriguing aspects to consider:

  • Polyfunctionality: The compound showcases multiple functional groups, including carboxylic acids and hydroxyl groups, which significantly enhance its potential for chemical reactivity and applications in various fields.
  • Naphthalene derivatives: Compounds that derive from naphthalene are often investigated for their biological activities, including antifungal, antibacterial, and even anti-cancer properties.
  • Pyrimidine importance: The pyrimidine structure is a well-known component of nucleic acids, making derivatives of this compound particularly valuable in medicinal chemistry and pharmaceutical research.
  • Thienyl substituent: The presence of the thienyl group introduces thiophene's unique properties, which can alter the electronic characteristics of the molecule and potentially lead to applications in organic electronics.

Moreover, compounds of this type often serve as intermediates in the synthesis of more complex structures or as ligands in coordination chemistry. As researchers continue to explore their properties, the potential for novel therapeutic agents remains a promising area of study. In the words of famed chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas," and this compound exemplifies the power of combining different chemical motifs to unlock new possibilities.

The intricate design of this compound also opens up exciting avenues for research in material science and medicinal chemistry, encouraging chemists to think outside the box and innovate solutions to contemporary challenges.

Synonyms
C34H30N2O6S
Spectrum_000880
Spectrum2_001304
Spectrum3_000892
Spectrum4_000986
KBioGR_001391
KBioSS_001360
DivK1c_000254
SPBio_001367
SCHEMBL7793068
CHEMBL3187835
KBio1_000254
KBio2_001360
KBio2_003928
KBio2_006496
KBio3_001804
NINDS_000254
NCGC00094552-04
PD055381
DB-045843
4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid;1-methyl-2-[2-(2-thienyl)vinyl]-5,6-dihydro-4H-pyrimidine
4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid,1-methyl-2-[(E)-2-thiophen-2-ylethenyl]-5,6-dihydro-4H-pyrimidine