Skip to main content

Clarithromycin

ADVERTISEMENT
Identification
Molecular formula
C38H69NO13
CAS number
81103-11-9
IUPAC name
4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid;3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine
State
State

Clarithromycin is a solid at room temperature. It is primarily available in tablet or pill form for oral administration.

Melting point (Celsius)
225.00
Melting point (Kelvin)
498.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
747.95g/mol
Molar mass
747.9510g/mol
Density
1.0410g/cm3
Appearence

Clarithromycin appears as a white to off-white crystalline powder. It is tasteless and practically odorless. This compound is typically supplied and used in its pure form for pharmaceutical applications.

Comment on solubility

Solubility of 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine

The solubility of a compound can significantly influence its application and effectiveness in various fields. For the compound with the chemical formula C38H69NO13, it is essential to consider several factors that dictate its solubility:

  • Polarity: The presence of functional groups such as carboxylic acids and hydroxyl groups typically increases water solubility due to their ability to form hydrogen bonds with water molecules.
  • Size of the molecule: The overall size of this compound, being a relatively large organic molecule, may introduce steric hindrance, potentially reducing solubility in aqueous solutions.
  • Hydrophobic regions: The naphthalene components contribute hydrophobic characteristics, which can further limit solubility in polar solvents.
  • pH dependence: The solubility may also vary with pH, especially for carboxylic acids, which can dissociate and enhance solubility in basic conditions.

In summary, while the functional groups present in 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid may suggest potential for solubility in water, the overall structural complexity and hydrophobic nature should be carefully evaluated. Understanding these solubility characteristics is crucial for predicting the behavior of the compound in different environments.

Interesting facts

Exploring 4-[(3-carboxy-2-hydroxy-1-naphthyl)methyl]-3-hydroxy-naphthalene-2-carboxylic acid; 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethyl-propan-1-amine

This intriguing compound, which combines a naphthalene backbone with a complex amine moiety, presents a fascinating subject for study due to its unique structural features and potential applications. Here are some compelling facts:

  • Diverse Applications: Compounds like this have been explored for their biological activity, especially in the field of medicinal chemistry. Compounds with naphthalene structures are often investigated for their antimicrobial, antifungal, and anti-inflammatory properties.
  • Chemical Complexity: The incorporation of multiple functional groups, such as carboxylic acids and hydroxyl groups, exemplifies the complexity in organic synthesis. Each functional group plays a pivotal role in determining the compound's reactivity and interactions with other molecules.
  • Research Significance: The study of naphthalene derivatives extends into material sciences, where they are utilized in creating synthetic dyes and polymers. Understanding the interactions of this compound with various substrates can provide insights into developing better materials.
  • Bioactivity Studies: The amine portion of the compound, specifically the dimethylpropan-1-amine unit, suggests potential activity at neurotransmitter receptors. This could lead to exploration in pharmacology for cognitive or mood disorders.
  • Synthesis Challenges: The synthesis of such multi-faceted molecules often requires advanced techniques in organic chemistry, including multi-step synthesis, protecting group strategies, and possibly even asymmetric synthesis to achieve the desired chiral centers.

As the field of chemistry continues to evolve, compounds like this hold promise for innovative research and development in various disciplines, underlining the importance of complex organic structures in both nature and synthetic applications. Each component tells a story of its own, contributing to the larger narrative of chemical research.

Synonyms
Imipramine pamoate
10075-24-8
Tofranil-PM
Imipramine embonate
EINECS 233-206-6
UNII-MC34P30298
MC34P30298
DTXSID80143484
5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-, pamoate
IMIPRAMINE EMBONATE (MART.)
IMIPRAMINE EMBONATE [MART.]
IMIPRAMINE PAMOATE (USP-RS)
IMIPRAMINE PAMOATE [USP-RS]
4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)-3-(10,11-dihydro-5H-dibenzo(b,f)azepin-5-yl)-N,N-dimethyl-1-propanamine (1:2)
IMIPRAMINE PAMOATE (USP MONOGRAPH)
IMIPRAMINE PAMOATE [USP MONOGRAPH]
DTXCID6065975
22540-17-6
233-206-6
Imipramine (pamoate)
4-[(3-carboxy-2-hydroxynaphthalen-1-yl)methyl]-3-hydroxynaphthalene-2-carboxylic acid;3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
4,4'-Methylenebis(3-hydroxy-2-naphthoic) acid, compound with 10,11-dihydro-N,N-dimethyl-5H-dibenz(b,f)azepine-5-propylamine (1:2)
4,4'-methylenebis[3-hydroxy-2-naphthoic] acid, compound with 10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propylamine (1
Tofranil-pm (TN)
Imipramine pamoate (USP)
IMIPRAMINE PAMOATE [MI]
CHEMBL3989845
SCHEMBL21834068
IMIPRAMINE PAMOATE [VANDF]
KAA07524
IMIPRAMINE EMBONATE [WHO-DD]
IMIPRAMINE PAMOATE [ORANGE BOOK]
DA-74453
HY-107956
CS-0030995
D08071
Q27283837