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Glycerol guaiacolate

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Identification
Molecular formula
C10H14O3
CAS number
93165-78-1
IUPAC name
4-(3-hydroxypropyl)-2-methoxy-phenol
State
State

At room temperature, glycerol guaiacolate is typically a solid. It exists as crystals that are relatively stable under standard conditions. The compound can be dissolved using various solvents and is used in pharmaceutical formulations as an expectorant.

Melting point (Celsius)
78.50
Melting point (Kelvin)
351.65
Boiling point (Celsius)
334.50
Boiling point (Kelvin)
607.65
General information
Molecular weight
196.23g/mol
Molar mass
196.2320g/mol
Density
1.1908g/cm3
Appearence

Appearance: Glycerol guaiacolate typically appears as a white to off-white crystalline powder. It may also appear in the form of a colorless to slightly yellow liquid if dissolved or melted. The compound is known for its pleasant aromatic smell, derived from the guaiac root, which is used to synthesize it.

Comment on solubility

Solubility of 4-(3-hydroxypropyl)-2-methoxy-phenol

The solubility of 4-(3-hydroxypropyl)-2-methoxy-phenol is influenced by its molecular structure and the presence of various functional groups. This compound contains both hydrophobic (the methoxy group) and hydrophilic (the hydroxypropyl group) segments, which can lead to varying solubility characteristics in different solvents.

Key Points Regarding Solubility:

  • Polar Solvents: The hydroxy group promotes solubility in polar solvents such as water, as it can form hydrogen bonds, increasing the compound's overall interaction with the solvent.
  • Non-polar Solvents: The methoxy group and aromatic ring render the compound somewhat soluble in non-polar solvents like hexane or toluene, though to a lesser extent.
  • Partial Solubility: Overall, 4-(3-hydroxypropyl)-2-methoxy-phenol may show limited solubility in pure water, but its solubility can be enhanced in aqueous mixtures or when forming complexes with other solutes.

In summary, understanding the solubility patterns can significantly impact the application of 4-(3-hydroxypropyl)-2-methoxy-phenol in various chemical processes and formulations. As such, performing solubility tests in different solvent systems is often recommended to optimize its use.

Interesting facts

Interesting Facts about 4-(3-hydroxypropyl)-2-methoxy-phenol

4-(3-hydroxypropyl)-2-methoxy-phenol, often referred to as a derivative of phenolic compounds, offers several intriguing aspects that make it noteworthy in both chemistry and applications.

Key Characteristics:

  • Antioxidant Properties: This compound is known for its potential antioxidant capabilities. It can scavenge free radicals, making it a valuable component in formulations aimed at reducing oxidative stress.
  • Applications in Skincare: Due to its antioxidant properties, 4-(3-hydroxypropyl)-2-methoxy-phenol is often utilized in cosmetics and skincare products. It helps to protect the skin from damage caused by environmental factors.
  • Flavor and Fragrance Industry: This compound has applications in the flavor and fragrance industry, where it can enhance the scent profiles of various products.
  • Research Significance: Scientists are exploring its use in various research fields, including pharmacology, given its potential therapeutic applications.

According to researchers, "The versatility of phenolic compounds is astonishing. They serve as a bridge between basic research and practical applications." This emphasizes the importance of 4-(3-hydroxypropyl)-2-methoxy-phenol in advancing both scientific understanding and practical utility.

Conclusion

In summary, 4-(3-hydroxypropyl)-2-methoxy-phenol is not only a fascinating compound but also a vital player in various industries, particularly in cosmetics and food. Its properties and applications underscore the significance of phenolic derivatives in enhancing everyday products and health.

Synonyms
Dihydroconiferyl alcohol
2305-13-7
4-(3-hydroxypropyl)-2-methoxyphenol
3-(4-HYDROXY-3-METHOXYPHENYL)-1-PROPANOL
4-hydroxy-3-methoxybenzenepropanol
guaiacyl propanol
NSC-4591
3-(4-guaiacyl)propanol
GUAIACYL-3-PROPANOL
L6399T797S
1-GUAIACYL-3-PROPANOL
CHEBI:4559
CONIFERYL ALCOHOL, DIHYDRO-
4-Hydroxy-3-methoxy-benzenepropanol
3-(4-hydroxy-3-methoxyphenyl)-propan-1-ol
3-(3-METHOXY-4-HYDROXYPHENYL)-1-PROPANOL
dhca
Benzenepropanol, 4-hydroxy-3-methoxy-
1-Propanol, 3-(4-hydroxy-3-methoxyphenyl)-
MFCD00016571
1-Propanol, 3-(4-hydroxy-3-methoxyphenyl)
dihydro-coniferyl alcohol
NSC 4591
4-(3-hydroxypropyl)-2-methoxy-phenol
Benzenepropanol, 4-hydroxy-3-methoxy- (9CI)
bmse000585
bmse010186
SCHEMBL200345
CHEMBL4207816
UNII-L6399T797S
DTXSID70177612
NSC4591
XH0861
AKOS005217790
CS-W017109
HY-W016393
SY057894
3-(3-Methoxy-4-hydroxyphenyl)propyl alcohol
F17046
EN300-1866116
BRD-K43807558-001-01-6
Q27106409