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CPPene

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Identification
Molecular formula
C8H17N2O5P
CAS number
151533-22-1
IUPAC name
4-(3-phosphonopropyl)piperazine-2-carboxylic acid
State
State

At room temperature, CPPene is a solid.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
266.21g/mol
Molar mass
266.2240g/mol
Density
1.5000g/cm3
Appearence

CPPene is typically a white crystalline powder.

Comment on solubility

Solubility of 4-(3-phosphonopropyl)piperazine-2-carboxylic acid

4-(3-phosphonopropyl)piperazine-2-carboxylic acid (C8H17N2O5P) demonstrates interesting solubility characteristics influenced by its unique molecular structure. Being an amino acid derivative containing both a phosphonic acid functionality and a carboxylic acid group, its solubility profile can be quite distinctive.

Factors Affecting Solubility:

  • Polarity: The presence of charged groups (such as -COOH and -PO₃H₂) increases the compound's polarity, enhancing its solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form multiple hydrogen bonds with water molecules further facilitates dissolution, making it soluble at various pH levels.
  • Chain Length: The hydrophobic piperazine ring contributes to overall solubility, though it may also lead to decreased solubility in non-polar solvents.

In aqueous solutions, it is likely to experience enhanced solubility due to interactions with water molecules, effectively dissociating into more soluble forms. As a result, one might say that "the more the phosphonic acid groups, the greater the solubility potential." This compound can find particular use in biochemical applications where solubility is critical.

Interesting facts

Interesting Facts About 4-(3-Phosphonopropyl)piperazine-2-carboxylic Acid

4-(3-phosphonopropyl)piperazine-2-carboxylic acid, commonly referred to in scientific circles for its unique structure and functionalities, presents fascinating opportunities in medicinal and agricultural chemistry. Here are some engaging aspects of this compound:

  • Phosphonate Group: The presence of a phosphonate functional group is significant. Phosphonates are known for their stability and are often utilized to mimic natural phosphates, making this compound particularly interesting for biological applications.
  • Applications in Drug Development: This compound has been studied for its potential use in pharmaceuticals, particularly in the search for treatments that target various types of cancers and infectious diseases. The modification of its piperazine backbone can lead to various derivatives with enhanced biological activity.
  • Agrochemical Potential: The phosphonate structure offers possibilities in the realm of plant protection chemicals and fertilizers. Researchers are exploring its capabilities to enhance nutrient absorption in plants.
  • Structure-Activity Relationships: The intricate balance of the carboxylic acid and phosphonopropyl groups opens avenues for investigations into structure-activity relationships (SAR), paving the way for the design of compounds with tailored properties for specific biological targets.
  • Research Significance: As a compound that can serve as a model for studying the interaction of phosphonates with biological macromolecules, it is often utilized in research to better understand drug design and mechanism of action.

With its multifaceted applications and structural uniqueness, 4-(3-phosphonopropyl)piperazine-2-carboxylic acid illustrates the intricate relationship between chemical structure and biological function. As scientists continue to explore its properties, who knows what innovative uses we may discover next?

Synonyms
100828-16-8
4-(3-phosphonopropyl)piperazine-2-carboxylic acid
(RS)-CPP
CARBOXYPEPTIDASE P
3-2-Cpp
2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-
(+/-)-CPP
3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
9075-64-3
4-(3-Phosphonopropyl)-2-piperazinecarboxylic acid
98Y1I8ZD4M
CHEMBL22304
DL-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
C8H17N2O5P
CPP, (+/-)-
2-Piperazinecarboxylic acid, 4-(3-phosphonopropyl)-, (+-)-
(+/-)-3-(2-CARBOXYPIPERAZIN-4-YL)-PROPYL-1-PHOSPHONIC ACID
4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid
3-(2-CARBOXYPIPERAZIN-4-YL)PROPYL-1-PHOSPHONATE
SR-01000075428
UNII-98Y1I8ZD4M
[3H]CPP
(+)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphoric Acid
(RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
(+/-)-CPP, solid
(y)-CPP
Lopac0_000322
SCHEMBL167788
( inverted question mark)-CPP
GTPL4082
(?)-CPP
DTXSID10905774
CUVGUPIVTLGRGI-UHFFFAOYSA-N
HMS3261A05
Tox21_500322
BDBM50002360
HB0036
MFCD00055136
AKOS024456756
CCG-204417
LP00322
SDCCGSBI-0050310.P002
(+/-)-2-HYDROXYTRIDECANOICACID
NCGC00015179-03
NCGC00015179-04
NCGC00015179-05
NCGC00024482-02
NCGC00024482-03
NCGC00261007-01
DA-68985
HY-100797
C-104
CS-0020444
EU-0100322
G82407
carboxypeptidase P from penicillium jan-thinellum
SR-01000075428-1
SR-01000075428-3
BRD-A60832661-001-01-8
Q27272147
(CPP)4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid
3-Phosphono-1-propyl-piperazine-2-carboxylic acid(DL-CPP)
4-(3-Phosphono-propyl)-piperazine-2-carboxylic acid (CPP)
(+/-)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
( inverted question mark)-3-(2-Carboxypiperazin-4-yl)propyl-1-phosphonic acid
624-824-0
634-473-5