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Epibatidine

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Identification
Molecular formula
C11H13N2
CAS number
140111-52-0
IUPAC name
4-(3-pyridyl)bicyclo[2.2.2]octan-1-amine
State
State

At room temperature, epibatidine is a solid. As a substance known for its potent pharmacological effects, it is typically handled in controlled environments.

Melting point (Celsius)
243.15
Melting point (Kelvin)
516.30
Boiling point (Celsius)
398.15
Boiling point (Kelvin)
671.30
General information
Molecular weight
208.31g/mol
Molar mass
208.3090g/mol
Density
1.1310g/cm3
Appearence

Epibatidine typically appears as a crystalline solid. It is a naturally occurring chemical compound, originally isolated from the skin of a certain species of poison dart frogs. The substance is usually handled in laboratories and research settings.

Comment on solubility

Solubility of 4-(3-pyridyl)bicyclo[2.2.2]octan-1-amine

The compound 4-(3-pyridyl)bicyclo[2.2.2]octan-1-amine exhibits interesting solubility characteristics that are worth exploring. Here are some key points to consider:

  • Polarity: The presence of the pyridine ring introduces a degree of polarity, which may enhance its solubility in polar solvents.
  • Hydrogen Bonding: As an amine, it has the potential to engage in hydrogen bonding, which can further influence its solubility in various solvents.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as ethanol or DMSO compared to non-polar solvents like hexane.
  • Aqueous Solubility: The solubility in water might be limited due to its complex structure, although the nitrogen in the amine could contribute some degree of solubility through interactions with water.

In summary, while the precise solubility profile of 4-(3-pyridyl)bicyclo[2.2.2]octan-1-amine is dependent on various factors, it is likely to favor solubility in polar solvents due to its structural features. This compound provides an intriguing study in solubility behavior, exemplifying how functional groups can significantly affect solubility in different media.

Interesting facts

Interesting Facts about 4-(3-Pyridyl)bicyclo[2.2.2]octan-1-amine

4-(3-Pyridyl)bicyclo[2.2.2]octan-1-amine is an intriguing compound that combines elements of organic chemistry with complex bicyclic structures. Here are some fascinating aspects of this compound:

  • Structural Complexity: The bicyclic structure of this compound allows for unique spatial arrangements, making it a focus of study in stereochemistry.
  • Biological Relevance: Compounds like 4-(3-Pyridyl)bicyclo[2.2.2]octan-1-amine are often explored for their potential as pharmacological agents, particularly in areas such as neuropharmacology due to their structural similarity to neurotransmitters.
  • Ligand Properties: The presence of the pyridine ring makes it a potential ligand for coordination chemistry, where it can interact with metal ions and form novel complexes.
  • Applications in Drug Design: Its unique bicyclic structure contributes to its utility in drug design, as it can interact with biological targets in ways that simpler structures cannot.
  • Therapeutic Potential: Research is ongoing into its potential applications in treating various disorders, particularly those affecting the central nervous system.

As a member of a larger class of bicyclic amines, 4-(3-Pyridyl)bicyclo[2.2.2]octan-1-amine showcases the beauty of chemical innovation and complexity. One might think of it as a bridge between basic structural science and advanced medicinal chemistry. As chemists continue to explore the nuances of this compound, its role in the development of new therapies may become increasingly significant.

Synonyms
GZ0I427OEC
UNII-GZ0I427OEC
1-pyridin-3-ylbicyclo[2.2.2]octan-4-amine
Pyridine, 3-(4-aminobicyclo(2.2.2)oct-1-yl)-
Bicyclo(2.2.2)octan-1-amine, 4-(3-pyridinyl)-
31293-00-2
4-(3-Pyridyl)bicyclo(2.2.2)octane-1-amine
DTXSID20274923
4-(3-PYRIDYL)BICYCLO(2.2.2)OCTAN-1-AMINE