Interesting facts
Interesting Facts about 4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid is a fascinating compound that exhibits unique properties and potential applications. Here are some noteworthy points about this intriguing chemical:
- Fluorine's Influence: The trifluoromethyl group attached to the aniline moiety significantly enhances the compound's lipophilicity and metabolic stability, which can lead to increased bioactivity in pharmacological applications.
- Biological Activity: Derivatives of pyridine carboxylic acids are well-known for their bioactivity, with potential roles in various therapeutic areas, including anti-cancer, anti-inflammatory, and anti-microbial properties.
- Versatility in Synthesis: This compound can be synthesized through multiple synthetic routes, making it a valuable intermediate in organic chemistry. Researchers can manipulate the synthesis to introduce various functional groups, tailoring it for specific applications.
- Research Frontiers: Current research is exploring its potential as a starting material for designing new pharmaceuticals and agrochemicals, highlighting its importance in medicinal chemistry.
- Environmental Impact: Understanding compounds like this one is vital in assessing their environmental behavior and potential toxicity, especially given the impact of fluorinated compounds in ecological systems.
- Analytical Techniques: This compound is often studied using state-of-the-art analytical techniques, such as NMR spectroscopy and mass spectrometry, which help elucidate its structure and confirm its purity in research and development settings.
In summary, 4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid encapsulates the intriguing intersection of organic chemistry, pharmacology, and environmental science. Its unique characteristics make it a compound worthy of investigation and study in various scientific fields.
Synonyms
TRIFLOCIN
13422-16-7
Triflocine
Triflocinum
Triflocina
S01B3A38SK
CL-65562
CL 65,562
DTXSID80864400
3-Pyridinecarboxylic acid, 4-((3-(trifluoromethyl)phenyl)amino)-
DTXCID70200414
4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
Triflocino
Triflocino [INN-Spanish]
Triflocin [USAN:INN]
Triflocine [INN-French]
Triflocinum [INN-Latin]
UNII-S01B3A38SK
TRIFLOCIN [INN]
Triflocin (USAN/INN)
TRIFLOCIN [USAN]
SCHEMBL3088829
CHEMBL2104493
4-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid
NLBIKXOJCISNQP-UHFFFAOYSA-N
AKOS017547980
NS00123783
D06230
Q27288373
Solubility of 4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
The solubility of 4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid, often referred to as a pyridine derivative, can be influenced by several factors due to its unique molecular structure. Here are some key points to consider:
In some studies, this compound has been shown to be sparingly soluble in water but readily soluble in organic solvents like dimethyl sulfoxide (DMSO) or ethanol. Thus, the choice of solvent is crucial when working with this chemical. Overall, while 4-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid exhibits limited solubility in water, its solubility characteristics reveal flexibility depending on environmental conditions.