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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
4-(3,5-dioxo-1,2-diphenyl-pyrazolidin-4-yl)-1,2-diphenyl-pyrazolidine-3,5-dione
State
State

Phenylbutazone is a solid at room temperature, generally found in powdered form.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.15
Boiling point (Celsius)
376.00
Boiling point (Kelvin)
649.15
General information
Molecular weight
308.37g/mol
Molar mass
308.3660g/mol
Density
1.2650g/cm3
Appearence

Phenylbutazone appears as a white or off-white crystalline powder. It is usually odorless and has a slightly bitter taste. The compound may sometimes show faint yellowish tint due to impurities or exposure to light.

Comment on solubility

Solubility of 4-(3,5-dioxo-1,2-diphenyl-pyrazolidin-4-yl)-1,2-diphenyl-pyrazolidine-3,5-dione

The solubility of the compound 4-(3,5-dioxo-1,2-diphenyl-pyrazolidin-4-yl)-1,2-diphenyl-pyrazolidine-3,5-dione is a significant aspect for its application in various fields. Solubility can greatly influence the bioavailability and efficacy of chemical compounds. Here are some key points to consider:

  • Polarity: The presence of numerous phenyl groups may suggest lower polarity. This typically results in lower solubility in polar solvents.
  • Solvent Interaction: The compound could be more soluble in organic solvents such as ethanol, acetone, or dimethyl sulfoxide (DMSO), which can solvate non-polar regions effectively.
  • Temperature Effect: As with many organic compounds, increasing temperature may enhance solubility, rendering it more versatile for experimental applications.
  • pH Dependence: Depending on the functional groups' protonation states, solubility may vary with changes in pH, impacting its dissolution in aqueous environments.

In summary, the solubility of this complex molecule is influenced by its hydrophobic character and the interactions with solvents. Understanding these properties is crucial for predicting its behavior in various chemical and biological processes.

Interesting facts

Interesting Facts about 4-(3,5-dioxo-1,2-diphenyl-pyrazolidin-4-yl)-1,2-diphenyl-pyrazolidine-3,5-dione

This complex compound, characterized by its multifaceted structure, belongs to the family of pyrazolidines, which are notable for their interesting pharmacological properties. Here are some engaging aspects of this compound:

  • Pharmaceutical Potential: Compounds with a pyrazolidine skeleton often exhibit anti-inflammatory and analgesic activities, making them a subject of research in pharmacology.
  • Structure Significance: The presence of two diphenyl groups and keto functionalities may enhance the compound's ability to engage in π-π stacking interactions, which are critical in biological systems.
  • Isomerism: Due to its complex structure, this compound can potentially exist in various isomeric forms, which can lead to different biological activities and properties, showcasing the richness of organic chemistry.
  • Role in Synthesis: The synthesis of such compounds can often involve intricate reaction pathways, providing insights into the reactivity of nitrogen-containing heterocycles.

As researchers delve deeper into the study of compounds like this, they uncover the potential for novel medicinal applications. The exploration of such structures illustrates the thrill of discovery in the world of organic chemistry.

In the words of renowned chemist Robert H. Grubbs, "The essence of chemistry is examining the world through the lens of molecules." This compound certainly exemplifies that sentiment.

Synonyms
Dipyraphene
Dipyrazolidinyl
Dipirazolidinile
3474-99-5
DA 381
Dipirazolidinile [Italian]
1,1',2,2'-Tetraphenyl-(4,4'-bipyrazolidine)-3,3',5,5'-tetrone
BRN 0376754
DTXSID40188295
5-26-14-00531 (Beilstein Handbook Reference)
(4,4'-BIPYRAZOLIDINE)-3,3',5,5'-TETRONE, 1,1',2,2'-TETRAPHENYL-
[4,4'-Bipyrazolidine]-3,3',5,5'-tetrone, 1,1',2,2'-tetraphenyl-
DTXCID70110786
uskavcmwcutatl-uhfffaoysa-n
4-(3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)-1,2-diphenylpyrazolidine-3,5-dione
SCHEMBL23295127
AKOS040751604