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Chenodeoxycholic acid

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Identification
Molecular formula
C24H40O4
CAS number
474-25-9
IUPAC name
4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
State
State

Chenodeoxycholic acid is a solid at room temperature. It typically presents in powder form.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.00
Boiling point (Celsius)
580.00
Boiling point (Kelvin)
853.00
General information
Molecular weight
392.57g/mol
Molar mass
392.5680g/mol
Density
1.1900g/cm3
Appearence

Chenodeoxycholic acid appears as a white crystalline powder. It is visually characterized by its crystalline nature and powdery texture.

Comment on solubility

Solubility of 4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

The solubility of the compound 4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid (C24H40O4) can be characterized by several key aspects:

  • Polarity: Due to the presence of multiple hydroxyl groups, the molecule exhibits a degree of polarity which can enhance its solubility in polar solvents.
  • Hydrogen Bonding: The hydroxyl groups are capable of forming hydrogen bonds, which generally increases solubility in water and other alcohols.
  • Hydrophobic Characteristics: The extensive aliphatic carbon chain contributes to hydrophobic interactions, which may limit solubility in purely aqueous environments.
  • Solvent Compatibility: This compound is likely to have good solubility in organic solvents such as ethanol and methanol, while being less soluble in hydrocarbons due to its complex structure.

In summary, while this compound presents challenges in solubility due to its hydrophobic characteristics, the presence of hydroxyl groups suggests that it will still be reasonably soluble in **polar organic solvents** and can engage in **hydrogen bonding**, aiding in its capacity to dissolve in various media.

Interesting facts

Interesting Facts About 4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

This remarkable compound, often referred to in literature as a bioactive molecule, represents a fascinating intersection of chemistry, biology, and medicinal applications. Here are some key points to ponder:

  • Biological Interest: Due to its unique molecular structure, this compound potentially interacts with various biological pathways, showcasing properties that could lead to therapeutic advancements.
  • Natural Origins: Substances with similar tetradecahydro structure are frequently derived from natural sources, making them valuable in drug discovery and development. Their biosynthesis can often be traced back to plant and animal metabolites.
  • Hydroxyl Groups: With three hydroxyl groups integrated into its structure, this compound exhibits opportunities for hydrogen bonding and reactivity, enhancing its solubility in biological media, which is important for its potential applications in pharmaceuticals.
  • Potential Applications: There could be applications ranging from anti-inflammatory properties to roles in hormone regulation, making this compound a candidate for therapeutic exploration.
  • Research Significance: Chemists and biochemists are particularly interested in understanding how such complex compounds interact within biological systems, leading to insights into their mechanisms of action.

As noted by many researchers, understanding the intricate details of such compounds can often lead to breakthroughs in various fields of study. In the words of a renowned chemist, "Every molecule tells a story; it’s our job to listen." Exploring the intricacies of compounds like 4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid is an exciting journey in unraveling the narrative of molecular interactions within life sciences.

Synonyms
GALL
3,7,12-Trihydroxycholan-24-oic acid
4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid
Bile acid
Choleinsaure
NSC657947
Acid, Cholic
Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha.,12.alpha.)-
4-(3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta(a)phenanthren-17-yl)pentanoic acid
Cholic acidfrom ox bile
12?-Hydroxyisocholic acid
3?,5?-Cholic acid-d5
Oprea1_388172
3.alpha.,7.alpha.,12.alpha.-Trihydroxy-5.beta.-cholanic acid
MLS001240272
SCHEMBL171402
BHQCQFFYRZLCQQ-UHFFFAOYSA-N
DTXSID201334862
HMS1678A18
HMS2233J24
HMS3371N03
ALBB-025014
BCP31486
QAA07387
WCA88364
AKOS000511084
LS-15079
NCI60_003386
SMR000768690
SY012968
cholan-24-oic acid, 3,7,12-trihydroxy-
L001220
Ursodeoxycholic Acid EP Impurity D;7-Epicholic acid;Ursocholate
4-(3,7,12-Trihydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoic acid