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PB-22

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Identification
Molecular formula
C23H30N2O4
CAS number
1400742-17-7
IUPAC name
4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one
State
State

At room temperature, PB-22 is a solid compound, typically encountered as a powder or crystalline solid, depending on its purity and specific formulation.

Melting point (Celsius)
220.30
Melting point (Kelvin)
493.45
Boiling point (Celsius)
548.45
Boiling point (Kelvin)
821.60
General information
Molecular weight
387.49g/mol
Molar mass
387.4850g/mol
Density
1.1650g/cm3
Appearence

PB-22 typically appears as a white powder in its pure form. It is often crystalline and can appear slightly different in appearance if impurities are present.

Comment on solubility

Solubility of 4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

The solubility of 4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one can be influenced by various factors, reflecting its chemical structure. This compound showcases a complex arrangement of both hydrophobic and hydrophilic characteristics, leading to varying solubility in different solvents.

Generally, we can assess its solubility through the following points:

  • Solvent Polarity: The presence of piperazine and methoxy groups suggests potential solubility in polar solvents like water and alcohols, though the overall solubility may not be very high.
  • Hydrophobic Interactions: The trimethoxyphenyl group contributes significant hydrophobic character, favoring solubility in nonpolar solvents such as dichloromethane or ethyl acetate.
  • Temperature Dependence: Elevated temperatures may enhance solubility due to increased molecular motion and interactions.

Quotes about solubility often emphasize that, "like dissolves like," meaning that polar molecules tend to dissolve in polar solvents, while nonpolar compounds prefer nonpolar environments. Thus, for this compound, one could expect a limited solubility profile. Experimentation in varying solvent systems would yield valuable insights into its comprehensive solubility behavior.

In summary, while 4-[4-(2-methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one is likely soluble in polar solvents to a certain degree, its hydrophobic components may limit this solubility, encouraging exploration in a range of different solvents for optimal results.

Interesting facts

Interesting Facts about 4-[4-(2-Methoxyphenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

This compound belongs to a class of molecules that have gained significant attention in the field of medicinal chemistry. Known for their potential therapeutic effects, this particular compound exhibits a fascinating blend of structural features that make it an interesting subject of study.

Key Features:

  • Structural Diversity: The compound incorporates a piperazine ring, which is a common motif in many pharmacologically active compounds. This enhances its ability to interact with biological targets.
  • Complex Substituents: The presence of methoxy groups (–OCH3) on both phenyl rings greatly influences the compound's electronic properties, potentially enhancing its pharmacokinetic profile.
  • Potential Applications: Compounds with similar structures have been investigated for their anti-depressant and anxiolytic properties, making this compound a candidate for further research in the treatment of mental health disorders.

One of the most intriguing aspects of this compound is its theoretical interactions with neurotransmitter systems in the brain. By modulating serotonin and dopamine pathways, it holds promise for improving mood and alleviating anxiety symptoms.

Research Insights:

  • Research suggests that the combination of methoxy substituents may confer enhanced lipophilicity, aiding in the ability of the compound to cross biological membranes.
  • It serves as an excellent model for designing new pharmaceuticals aimed at targeting psychiatric conditions.
  • The synthetic pathways to create such compounds can lead to further innovations in drug design and medicinal chemistry.

As scientists continue to explore the therapeutic potentials of this compound, the emphasis lies on understanding the balance between efficacy and safety. The synthesis and exploration of similar compounds not only expand our arsenal in drug discovery but also deepen our understanding of chemical interactions within biological systems.

This compound exemplifies the interface between chemistry and pharmacology, showcasing how structural modifications can lead to profound differences in biological activity.