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Eltrombopag Olamine

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Identification
Molecular formula
C24H28Cl2N2O2
CAS number
496775-62-3
IUPAC name
[4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]-phenyl-methanone;dichloride
State
State

At room temperature, Eltrombopag Olamine is typically found in a solid state.

Melting point (Celsius)
254.10
Melting point (Kelvin)
527.30
Boiling point (Celsius)
294.10
Boiling point (Kelvin)
567.30
General information
Molecular weight
442.87g/mol
Molar mass
442.8700g/mol
Density
1.3000g/cm3
Appearence

This compound is typically a white to off-white solid powder. It is crystalline in nature.

Comment on solubility

Solubility of [4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]-phenyl-methanone;dichloride

The solubility of this compound, which possesses significant ionization due to the presence of the morpholinium and piperidin-ium cations, can be quite fascinating. Generally, the solubility of ionic compounds like this one depends on several factors:

  • Polarity: Due to its ionic nature, it is likely to be soluble in polar solvents such as water.
  • Hydrogen Bonding: The morpholinium group can engage in hydrogen bonding, further enhancing solubility in polar environments.
  • Counterions: The presence of chloride ions may contribute to increased solubility due to the favorable interactions with the surrounding solvent.
  • Temperature: As with many compounds, solubility may increase with higher temperatures, facilitating dissociation and interaction with solvent molecules.

In contrast, solubility may be reduced in non-polar solvents due to the lack of favorable interactions. As a result, “the more polar the solvent, the greater the solubility” tends to hold true for ionic compounds such as this one.

Overall, while precise solubility data may be required for practical applications, this compound is expected to exhibit appreciable solubility in polar solvents, making it potentially useful in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts About [4-[4-(2-morpholin-4-ium-4-ylethyl)phenyl]piperidin-1-ium-1-yl]-phenyl-methanone;dichloride

This unique compound holds a notable position in the field of chemistry due to its structural complexity and potential applications. Here are some intriguing highlights:

  • Molecular Diversity: The compound integrates a morpholine ring and a piperidine system, contributing to its diverse chemical behavior and interactions.
  • Pharmaceutical Potential: Compounds with similar structures have been researched for their abilities as potential therapeutic agents, particularly in targeting neurological disorders.
  • Interactions: The structural components allow for various interactions, making this compound a candidate for studying ligand-receptor relationships in biochemical pathways.
  • Research Relevance: Its quaternary ammonium nature enhances its solubility in biological systems, which is crucial for drug design.
  • Complex Chemical Behavior: The presence of multiple aromatic rings in its structure often leads to interesting photophysical properties, warranting further exploration.

As noted in scientific literature, "the intricate design of such piperidine derivatives navigates the intersection of medicinal chemistry and organic synthesis, yielding valuable insights into molecular design and function." The exploration of compounds like this one can lead to enhanced drug development strategies and improved therapeutic options in the future.

Overall, this compound exemplifies the beauty of complex organic chemistry and its promising pathways toward innovative scientific advancements.

Synonyms
1-(2-Morpholinoethyl)-4-phenyl-4-piperidyl phenyl ketone dihydrochloride
KETONE, 1-(2-MORPHOLINOETHYL)-4-PHENYL-4-PIPERIDYL PHENYL, DIHYDROCHLORIDE
25224-24-2
RefChem:350379