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Identification
Molecular formula
C21H21N3O2
CAS number
.null
IUPAC name
4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde
State
State

At room temperature, 4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde is typically in a solid state.

Melting point (Celsius)
212.00
Melting point (Kelvin)
485.15
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.15
General information
Molecular weight
355.41g/mol
Molar mass
355.4130g/mol
Density
2.2500g/cm3
Appearence

The compound is a crystalline solid, typically white or off-white in appearance.

Comment on solubility

Solubility of 4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde

The solubility of the compound 4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde, with its chemical formula C21H21N3O2, presents intriguing characteristics that warrant exploration.

In general, the solubility of organic compounds can depend on several factors, including:

  • Polarity: Polar compounds are typically soluble in polar solvents, while non-polar compounds favor non-polar solvents.
  • Hydrogen bonding: The presence of functional groups that can form hydrogen bonds can increase solubility in polar solvents.
  • Molecular size: Larger molecules may have reduced solubility due to increased steric hindrance.

For C21H21N3O2, one might anticipate that its moderate size and the presence of nitrogen and oxygen atoms could allow it to exhibit some degree of solubility in various solvents. Specifically:

  • It may dissolve well in polar organic solvents such as dichloromethane or dimethyl sulfoxide (DMSO).
  • Its solubility in water might be limited due to the relatively large hydrophobic phenyl and indole structures.

In conclusion, while the precise solubility profile of 4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde is not definitively established without experimental data, its structural complexity suggests that it may exhibit selective solubility patterns, especially in organic solvents.

Interesting facts

Interesting Facts about 4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde

This intriguing compound, often referred to in scientific communities for its unique structural attributes, showcases a fascinating blend of functional groups that contribute to its chemical behavior and potential applications. Here are some noteworthy facts:

  • Piperazine Core: The presence of the piperazine ring is particularly significant, as it is known for its role in numerous pharmacological applications, including anxiolytic and antidepressant effects.
  • Indolinone Derivative: The indolinone moiety featured in this compound is noteworthy. It is prevalent in various biologically active compounds, leading to its investigation in fields like medicinal chemistry and drug development.
  • Potential Applications: Due to its unique structure, this compound could have potential applications in:
    • Neuroscience – targeting specific neural pathways.
    • Pharmaceutical development – as a lead compound in designing novel medications.
    • Material science – exploring its use in functional materials due to its interesting electronic properties.
  • Mechanistic Insights: Understanding the interactions of this compound at the molecular level can provide insights into how it affects biological systems, making it a subject of interest in drug-receptor interaction studies.
  • Research Potential: As research continues, compounds with complex structures like this one may yield new insights into their mechanisms of action, allowing for the development of targeted therapies with fewer side effects.

In conclusion, 4-[4-[(2-oxoindolin-3-yl)methyl]phenyl]piperazine-1-carbaldehyde represents an amalgamation of synthetic complexity and biological potential, making it a captivating subject for further exploration in the realm of chemistry and pharmacology.

Synonyms
3-[4-(1-formylpiperazin-4-yl)-benzylidenyl]-2-indolinone
4-{4-[(2-oxo-2,3-dihydro-1h-indol-3-yl)methyl]phenyl}piperazine-1-carbaldehyde
3-(4-(1-Formylpiperazin-4-yl)-benzylidenyl)-2-indolinone
4-(4-((2-oxo-2,3-dihydro-1H-indol-3-yl)methyl)phenyl)piperazine-1-carbaldehyde
4-[4-[(2-oxo-1,3-dihydroindol-3-yl)methyl]phenyl]piperazine-1-carbaldehyde
DB02058
PD060257
Q27465491
4-(4-{[(3R)-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)piperazine-1-carbaldehyde