Fluorophenylpiperidinobutanone | Solubility of Things

Identification

Molecular formula

C₂₆H₂₈ClFN₂O₂

CAS number

181289-15-6

IUPAC name

4-[4-(3-chlorophenyl)-4-(pyrrolidine-1-carbonyl)-1-piperidyl]-4-fluoro-1-phenyl-butan-1-one

State

At room temperature, this compound is a solid.

Melting point (Celsius)

89.00

Melting point (Kelvin)

362.15

Boiling point (Celsius)

537.12

Boiling point (Kelvin)

810.27

General information

Molecular weight

438.95g/mol

Molar mass

438.9500g/mol

Density

1.2478g/cm³

Appearence

This compound typically presents as a white to off-white solid when isolated in its pure form. It may occasionally appear as a powder or crystalline substance, depending on the method of preparation and purification.

Comment on solubility

Solubility of 4-[4-(3-chlorophenyl)-4-(pyrrolidine-1-carbonyl)-1-piperidyl]-4-fluoro-1-phenyl-butan-1-one

The solubility of the compound 4-[4-(3-chlorophenyl)-4-(pyrrolidine-1-carbonyl)-1-piperidyl]-4-fluoro-1-phenyl-butan-1-one, with its complex structure, can be influenced by multiple factors. Here are some key points to consider:

Polarity: The presence of multiple functional groups can affect the polarity of the compound significantly, thus impacting its solubility in different solvents.
Solvent Type: This compound may show varying solubility in water versus organic solvents, with a tendency to be more soluble in non-polar or moderately polar solvents.
Hydrogen Bonding: Potential hydrogen bonding sites in the structure could enhance solubility in certain polar solvents.
Temperature Influence: Like many organic compounds, solubility can increase with temperature; thus, higher temperatures may improve dissolution rates.

As a general guide, *"the solubility of a compound relies heavily on its structure and the nature of the solvent."* To ascertain precise solubility characteristics, empirical measurements and specific solvent interactions may be necessary.

To summarize, understanding the solubility of this compound involves a careful assessment of its chemical properties and the context of the solvent used.

Interesting facts

Interesting Facts about 4-[4-(3-chlorophenyl)-4-(pyrrolidine-1-carbonyl)-1-piperidyl]-4-fluoro-1-phenyl-butan-1-one

This complex chemical compound is notable for its intricate structure and potential applications in medicinal chemistry. As a scientist studying such compounds, understanding their behavioral characteristics in biological systems can be both fascinating and critical. Here are some key facts:

Structural Complexity: The compound features multiple functional groups, including a fluorinated moiety and a chlorophenyl group, which may influence its reactivity and interaction with biological targets.
Potential Pharmacological Uses: Due to its structure, this compound may exhibit interesting pharmacological properties that could be beneficial in drug discovery, particularly in the realm of neuropharmacology.
Importance of Substitution Patterns: The presence of substituents like the chlorophenyl and piperidyl rings could lead to varying biological activities, highlighting the importance of *structure-activity relationships* (SAR) in medicinal chemistry.
Research Opportunities: This compound may serve as a lead compound for further modifications to enhance efficacy and selectivity against specific biological targets.
Future Directions: Investigating the compound's mechanism of action and metabolic pathways could open avenues for further exploration in therapeutic applications, particularly in treating neuropsychiatric disorders.

As the field of medicinal chemistry continues to evolve, compounds like this serve as essential bridges between *chemical synthesis* and *therapeutic development*. Scientists are encouraged to delve deeper into the unique structural attributes and potential biological implications of such compounds, paving the way for innovative treatments and better understanding of complex diseases.