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Identification
Molecular formula
C20H14IN3OS
CAS number
183322-17-0
IUPAC name
4-[4-(3-iodophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine
State
State

At room temperature, 4-[4-(3-iodophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine is typically found in a solid state, manifesting mainly as a crystalline material. This state is stable at standard environmental conditions, including room temperature and pressure.

Melting point (Celsius)
173.40
Melting point (Kelvin)
446.55
Boiling point (Celsius)
537.20
Boiling point (Kelvin)
810.35
General information
Molecular weight
457.30g/mol
Molar mass
457.3040g/mol
Density
1.6700g/cm3
Appearence

This compound is typically observed as a white to off-white crystalline solid. Its appearance may vary slightly depending on the purity and form (such as powder or crystalline chunks). The crystals or solid form may take on different shades or refinements but generally adhere to this description.

Comment on solubility

Solubility of 4-[4-(3-iodophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine

The solubility of the compound 4-[4-(3-iodophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine (C20H14IN3OS) can be quite complex due to its molecular structure. Several factors influence the solubility of this compound:

  • Molecular Interactions: The presence of the iodine atom and sulfinyl group may enhance solubility in polar solvents.
  • Hydrophobic and Hydrophilic Character: The aromatic rings contribute to hydrophobic interactions which may limit solubility in water, while the pyridine nitrogen provides potential hydrogen bonding, enhancing solubility in some organic solvents.
  • Temperature and pH Dependence: Solubility can vary with temperature and pH. Generally, higher temperatures can increase solubility.

As a result of these factors, this compound may exhibit:

  • Limited solubility in aqueous solutions, making it more suited for organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Solubility influenced by concentration, leading to potential variations in solubility with different formulations.

In conclusion, the solubility profile of this compound is not straightforward, and further investigation is often necessary to determine the best solvents and conditions for its application in research and industry. Understanding these solubility characteristics is crucial for its effective utilization.

Interesting facts

Interesting Facts about 4-[4-(3-Iodophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine

This complex compound is an intriguing example of the intersection between organic chemistry and medicinal applications. Here are some captivating points regarding this compound:

  • Multi-functional Groups: The presence of various functional groups such as an imidazole ring, pyridine, and a sulfinyl moiety suggests potential biological activity.
  • Pharmaceutical Potential: Compounds like this one often exhibit significant pharmacological properties, making them subjects of interest in drug discovery and development.
  • Halogen Influence: The incorporation of iodine can greatly influence the compound’s reactivity and biological interaction due to the unique characteristics of halogens.
  • Aromatic Systems: The multiple aromatic rings within the structure contribute to its stability and the likelihood of engaging in crucial π-π interactions, which can enhance binding affinity in biological systems.
  • Imidazole's Role: Imidazole is known for its ability to stabilize certain active sites in enzymes, indicating that derivatives of this compound might be useful in enzyme inhibition or modulation.

As noted by researchers in the field, "The structural diversity in compounds like these provides a wealth of opportunities for modifications leading to novel therapeutic agents." Thus, 4-[4-(3-iodophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine could be pivotal in advancing our understanding of drug interactions and the development of new treatments.

Synonyms
erk000253
4-(4-(3-Iodophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridine
SCHEMBL155371
CHEMBL5303502
SCHEMBL21068026
BDBM92007
BDBM225383
HSCI1_000175
PD037247
189319-35-5