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Bis[4-(4-aminophenoxy)phenyl]sulfone

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Identification
Molecular formula
C24H20N2O4S
CAS number
30215-96-2
IUPAC name
4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline
State
State

This compound is typically a solid at room temperature.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
655.00
Boiling point (Kelvin)
928.15
General information
Molecular weight
396.49g/mol
Molar mass
396.4610g/mol
Density
1.3600g/cm3
Appearence

This compound typically appears as an off-white or pale yellow crystalline solid.

Comment on solubility

Solubility of 4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline

The solubility of 4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline can be quite intricate due to its complex molecular structure. Here are some key points to consider:

  • Solvent Compatibility: This compound may exhibit variable solubility depending on the solvent used. Polar solvents, such as water and methanol, might enhance solubility because of potential hydrogen bonding interactions.
  • Temperature Influence: Increasing the temperature typically increases solubility for many organic compounds. Therefore, heating the solvent that it is dissolved in could facilitate better solubility.
  • Functional Groups: The presence of both amino and sulfonyl groups suggests that intermolecular interactions, like hydrogen bonding, could significantly influence its solubility.
    These groups may interact with water, indicating potential for solubility in aqueous environments.
  • pH Dependence: Being an amine, its solubility might also change with the pH of the solution. In more acidic conditions, it may become protonated, potentially enhancing its solubility in water.

In summary, while the solubility of 4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline may not be readily predictable, understanding its structural features and the chemical nature of potential solvents can lead to significant insights in its solubility behavior.

Interesting facts

Interesting Facts about 4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline

This compound, often recognized in the field of medicinal chemistry, showcases the intricate relationship between structure and function. Here are some fascinating insights:

  • Chemical Complexity: The architecture of this compound is quite intricate, incorporating multiple aromatic rings connected by sulfonyl and amino groups. Such complexity is noteworthy as it may lead to unique biochemical interactions.
  • Biological Activity: Compounds with similar structures often exhibit significant biological activity. They can act as potential inhibitors in various biological pathways, which makes them candidates for drug development in areas like cancer therapy.
  • Versatile Functional Groups: The presence of –NH₂ (amino) and –SO₂ (sulfonyl) groups enhances the compound’s reactivity. This versatility is crucial for chemists working on modifications to improve efficacy or bioavailability.
  • Research Applications: Due to its structural characteristics, this compound can serve as a model for studying the interactions between target proteins and small molecules, aiding in the design of more effective pharmaceuticals.
  • Intriguing Synthesis: The synthesis of such compounds often demands advanced synthetic strategies. Techniques such as multi-step synthesis and specific coupling reactions are vital, showcasing the skills of the organic chemist.

To quote renowned chemist Martin Gouterman, "The beauty of a molecule is not only in its composition but in how it behaves in various chemical landscapes." This compound epitomizes this sentiment, being a testament to the marvels of synthetic organic chemistry and its potential impact on human health.


In summary, 4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline is a prime example of how molecular design can lead to advancements in pharmaceuticals, further highlighting the importance of chemistry in addressing health challenges.

Synonyms
Benzenamine, 4,4'-[sulfonylbis(4,1-phenyleneoxy)]bis-
Benzenamine, 4,4'-(sulfonylbis(4,1-phenyleneoxy))bis-
DTXSID1065344
4,4'-(Sulphonylbis(4,1-phenyleneoxy))dianiline
4,4'-[Sulfonylbis(4,1-phenyleneoxy)]bis[benzenamine]
4,4'-[sulphonylbis(4,1-phenyleneoxy)]dianiline
4,4'-(Sulfonylbis(4,1-phenyleneoxy))bis(benzenamine)
DTXCID2033996
235-986-3
13080-89-2
Bis[4-(4-aminophenoxy)phenyl]sulfone
Bis[4-(4-aminophenoxy)phenyl] Sulfone
4,4'-((Sulfonylbis(4,1-phenylene))bis(oxy))dianiline
4-[4-[4-(4-aminophenoxy)phenyl]sulfonylphenoxy]aniline
Bis(4-aminophenoxyphenyl)sulfone
4,4'-Sulfonylbis(4-phenyleneoxy)dianiline
Aniline, 4,4'-(sulfonylbis(p-phenyleneoxy))di-
Bis(4-(4-aminophenoxy)phenyl)sulfone
Sulfonyl diamine
ANILINE, 4,4'-SULFONYLBIS(4-PHENYLENEOXY)DI-
4,4'-((Sulfonylbis(4,1-phenylene))-bis(oxy))dianiline
4-{4-[4-(4-aminophenoxy)benzenesulfonyl]phenoxy}aniline
EINECS 235-986-3
BRN 2186439
4,4'-(Sulfonylbis(4,1-phenyleneoxy))bisbenzenamine
MFCD00039155
PR45R88ZGB
Oprea1_330518
SCHEMBL65653
CBDivE_006384
SCHEMBL809616
STK366521
AKOS005443017
BS-42112
DB-411787
B1682
NS00024128
ST50907559
D88842
4,4'-[sulfonylbis(1,4-phenyleneoxy)]dianiline
4,4'-[Sulfonylbis(4,1-phenyleneoxy)]dianiline
4,4'-[sulfonylbis(benzene-4,1-diyloxy)]dianiline
4-(4-([4-(4-Aminophenoxy)phenyl]sulfonyl)phenoxy)aniline #
4-(4-{[4-(4-AMINOPHENOXY)PHENYL]SULFONYL}PHENOXY)ANILINE
4-(4-aminophenoxy)-1-{[4-(4-aminophenoxy)phenyl]sulfonyl}benzene