Skip to main content

Montelukast

ADVERTISEMENT
Identification
Molecular formula
C35H36ClNO3S
CAS number
151767-02-1
IUPAC name
4-[4-[(4-chlorophenyl)-(2-pyridyl)methoxy]-1-piperidyl]butanoic acid
State
State

Montelukast is a solid at room temperature, commonly dispensed in tablet or granule form.

Melting point (Celsius)
137.00
Melting point (Kelvin)
410.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
586.19g/mol
Molar mass
586.1860g/mol
Density
1.4000g/cm3
Appearence

Montelukast is typically found as a white to off-white powder. It is often formulated into tablets or granules intended for oral administration.

Comment on solubility

Solubility of 4-[4-[(4-chlorophenyl)-(2-pyridyl)methoxy]-1-piperidyl]butanoic acid

The solubility of the compound 4-[4-[(4-chlorophenyl)-(2-pyridyl)methoxy]-1-piperidyl]butanoic acid, with the chemical formula C35H36ClNO3S, is an intriguing topic due to its complex structure. This compound is likely to exhibit varied solubility characteristics depending on the solvent used. Here are some key points to consider:

  • Polar solvents: Given the presence of the carboxylic acid functional group, this compound may show better solubility in polar solvents such as water or methanol.
  • Non-polar solvents: The large hydrophobic portions of the molecule, primarily arising from the substituted phenyl and pyridyl groups, may lead to higher solubility in non-polar organic solvents like chloroform or hexane.
  • pH dependence: The solubility may also vary with pH; in acidic conditions, the carboxylic acid group remains protonated which could enhance its solubility in aqueous environments.
  • Temperature effects: Generally, an increase in temperature tends to improve the solubility of most organic compounds, and this compound may follow that trend.

Ultimately, the interplay between its hydrophilic and hydrophobic characteristics makes this compound particularly interesting, and its solubility profile could offer valuable insights into its behavior in various chemical environments. As noted, "The nature of solubility is a dance between forces, seeking balance in a world of contrasts."

Interesting facts

Interesting Facts About 4-[4-[(4-chlorophenyl)-(2-pyridyl)methoxy]-1-piperidyl]butanoic acid

This compound, commonly known in pharmaceutical research, is gaining attention for its potential therapeutic applications. Here are some engaging insights:

  • Complex Structure: The molecule features a multifaceted structure consisting of aromatic rings, a piperidine moiety, and a butanoic acid backbone, showcasing the intricate designs that chemists can create in the laboratory.
  • Pharmacological Potential: Due to the presence of the piperidine ring and various aromatic substituents, this compound may exhibit significant pharmacological activity, particularly in the modulation of neurotransmitter systems.
  • Role of Chlorine: The inclusion of the chlorophenyl group not only enhances the lipophilicity of the compound but may also affect its binding affinity to biological targets, making it a subject of interest in drug design.
  • Pyridine Influence: The pyridyl group can participate in various interactions, such as hydrogen bonding and π-π stacking, which are critical for the compound's biological activity.
  • Research Applications: Scientists are exploring the potential of this compound in the development of new pharmaceuticals, particularly in targeting neurological disorders and other conditions.

The research surrounding compounds like this one demonstrates the endless possibilities in medicinal chemistry. As noted by experts in the field, "The complexity of a compound often reflects its potential." This statement embodies the excitement surrounding such unique chemical structures!

Synonyms
1070505-53-1
4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoic acid
rac Bepotastine
190786-43-7
TAU-284DS
4-{4-[(4-chlorophenyl)(pyridin-2-yl)methoxy]piperidin-1-yl}butanoic acid
4-[(4-Chlorophenyl)-2-pyridinylmethoxy]-1-piperidinebutanoic Acid;4-[4-[(4-Chlorophenyl)(2-pyridyl)methoxy]piperidino]butanoic Acid;DB 185
SCHEMBL726880
CHEMBL4877190
DTXSID70869727
YWGDOWXRIALTES-UHFFFAOYSA-N
(+)-(S)-4-[4-[1-(4-chlorophenyl)-1-(2-pyridyl)methoxy]piperidin-1-yl]butyric acid4-[4-[(S)-(4-chlorophenyl)-pyridin-2-ylmethoxy]piperidin-1-yl]butanoic acid
AKOS040759286
DB04890
SB17504
DB-241591
CS-0005697
EN300-19768653
4-(4-[(4-chlorophenyl)-2-pyridylmethoxy]piperidinyl)butanoic acid
4-[4-[(4-chlorophenyl)-2-pyridylmethoxy]-1-piperidyl]butanoic acid
4-(4-((4-chlorophenyl)(pyridin-2-yl)methoxy)piperidin-1-yl)butanoicacid
4-{4-[(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-piperidinyl}butanoi c acid
4-{4-[(4-Chlorophenyl)(2-pyridinyl)methoxy]-1-piperidinyl}butanoic acid