Fluorophenylpiperazine Trimethoxyphenylbutanone

Identification

Molecular formula

C₂₃H₂₉FN₂O₄

CAS number

956136-97-1

IUPAC name

4-[4-(4-fluorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

State

At room temperature, this compound is typically in a solid state, often found as a crystalline powder or solid.

Melting point (Celsius)

175.00

Melting point (Kelvin)

448.15

Boiling point (Celsius)

525.50

Boiling point (Kelvin)

798.65

General information

Molecular weight

398.46g/mol

Molar mass

398.4580g/mol

Density

1.3000g/cm³

Appearence

The compound is generally a crystalline solid with a white to off-white appearance. It can form fine powder or small crystalline flakes.

Comment on solubility

Solubility of 4-[4-(4-fluorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

The solubility of 4-[4-(4-fluorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one can be particularly interesting due to its complex structure. Here are several key points regarding its solubility:

Polarity: Being a compound with multiple functional groups, including a piperazine moiety and trimethoxyphenyl groups, its polarity is influenced primarily by the presence of these groups.
Solvent Preference: This compound may exhibit good solubility in organic solvents such as ethanol, methanol, and DMSO, while being less soluble or insoluble in water due to its hydrophobic characteristics.
Complex Interactions: Its solubility may also be affected by intermolecular forces which include hydrogen bonding and π-π stacking interactions with various solvents.
Temperature Dependency: Solubility can vary with temperature; generally, increasing temperature can lead to increased solubility in most solvents, making it essential for practical applications.

To summarize, the solubility of 4-[4-(4-fluorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one is complex and dependent on several factors, including its structural characteristics, the choice of solvent, temperature, and potential interactions. Understanding these factors is crucial for optimization in various applications.

Interesting facts

Interesting Facts about 4-[4-(4-Fluorophenyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

This compound stands out in the field of medicinal chemistry due to its unique structural properties and potential therapeutic applications. Here are some engaging insights about this intriguing molecule:

Multi-functional Potential: With its intricate architecture, the compound combines elements that can interact with multiple biological targets, making it a candidate for the development of novel pharmaceuticals.
Pharmacophore Analysis: The presence of the piperazine ring has been associated with various biological activities, including antipsychotic and antidepressant properties, making this compound particularly interesting for mental health research.
Fluorine Influence: The incorporation of the 4-fluorophenyl group enhances the lipophilicity of the molecule, which can improve its pharmacokinetic profile. This substitution is known to optimize drug efficacy and bioavailability significantly.
Multi-methoxy Substitution: The presence of three methoxy groups on one of its phenyl moieties is noteworthy. Methoxy groups can increase solubility and bioactivity, contributing to the compound's potential therapeutic effectiveness.
Synthesis and Research: The synthesis of this compound can be carried out through various organic reactions, making it a fascinating subject of study for synthetic chemists. Its synthesis routes often involve complex multi-step procedures that challenge chemists and enhance their expertise in reaction conditions.

This compound not only illustrates the beauty of organic chemistry through its structural complexity but also embodies the promises of medicinal chemistry, where such compounds can lead to breakthroughs in treatment modalities. As researchers delve deeper into this compound, its potential might open new avenues in therapeutic strategies.