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Lasofoxifene

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Identification
Molecular formula
C28H30O4
CAS number
83166-56-3
IUPAC name
4-[[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl]-1,3-dioxolan-2-one
State
State

At room temperature, lasofoxifene is in a solid state, typically available as a crystalline powder suitable for medical formulations.

Melting point (Celsius)
188.50
Melting point (Kelvin)
461.65
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.00
General information
Molecular weight
441.53g/mol
Molar mass
441.5250g/mol
Density
1.3200g/cm3
Appearence

Lasofoxifene appears as a white to off-white crystalline powder. It is practically insoluble in water, but soluble in some organic solvents.

Comment on solubility

Solubility of 4-[[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl]-1,3-dioxolan-2-one

The solubility of a compound like 4-[[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl]-1,3-dioxolan-2-one can provide significant insights into its potential applications and behaviors in various environments. While specific solubility data may vary, several factors generally influence its solubility:

  • Molecular Structure: The complex structure of this compound, including the dioxole and phenyl groups, can affect its interaction with solvents.
  • Polarity: Compounds with high aromatic content, like this one, might exhibit lower solubility in polar solvents and higher solubility in non-polar solvents.
  • Temperature: As with many organic compounds, solubility may increase with temperature, allowing for greater dissolution in certain solvents at elevated temperatures.
  • pH Levels: The presence of functional groups may lead to pH-dependent solubility, which can greatly vary under different conditions.

To summarize, the solubility of 4-[[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl]-1,3-dioxolan-2-one is likely to be influenced by its complex structure and the nature of the solvent used. Understanding these aspects is crucial for predicting its reactivity and stability in various chemical processes.

Interesting facts

Interesting Facts about 4-[[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl]-1,3-dioxolan-2-one

This compound, a complex organic molecule, is rich in interesting features that make it a subject of study for chemists and pharmacologists alike. Here are some engaging facts about this unique compound:

  • Diverse Applications: This compound falls under the category of dioxolanes, which are often investigated for their potential as pharmaceuticals and agrochemicals. Its structure suggests significant bioactivity, making it a candidate for further study in drug formulation.
  • Structural Complexity: The intricate arrangement of rings and functional groups provides a fascinating glimpse into synthetic organic chemistry. The presence of methoxy and phenyl groups indicates it may exhibit interesting electronic properties as well.
  • Potential Biological Activity: Compounds similar to this structure have been noted for their effectiveness in various biomedical applications. Researchers speculate that this could lead to novel therapies, particularly in fields like oncology or neurology.
  • Research Interest: Increased interest in compounds with phenolic groups stems from their antioxidant properties, suggesting that this compound may also contribute to health-related benefits.
  • Synthetic Pathways: The synthesis of such complex molecules informs chemists about the challenges and methods used in organic synthesis, highlighting techniques such as multi-step synthesis and functional group manipulation.

As noted by many chemists, "The beauty of chemistry lies not only in the molecules themselves but also in the stories they tell about nature and our ability to manipulate it." The study of 4-[[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl]-1,3-dioxolan-2-one exemplifies this idea, encouraging further exploration and understanding of its properties and potential applications.

Synonyms
WXG3AWS2BN
3-(p-(3,4-Dihydro-6-methoxy-2-phenyl-1-naphthyl)phenoxy)-1,2-propanediol cyclic carbonate
4350-02-1
Carbonic acid, cyclic ((p-(6-methoxy-2-phenyl-3,4-dihydro-1-naphthyl)phenoxy)methyl)ethylene ester
BRN 1607853
UNII-WXG3AWS2BN
SCHEMBL14895192
DTXSID50963015
1-(p-(2,3-Dihydroxypropoxy)phenyl)-2-phenyl-6-methoxy-3,4-dihydronaphthalene cyclic carbonate
Q27292999
4-{[4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)phenoxy]methyl}-1,3-dioxolan-2-one