Skip to main content

3,4-Dichloroaniline

ADVERTISEMENT
Identification
Molecular formula
C6H5Cl2N
CAS number
95-76-1
IUPAC name
4-(4-amino-3-chloro-phenyl)-2-chloro-aniline
State
State

At room temperature, 3,4-Dichloroaniline is typically found in a solid state.

Melting point (Celsius)
74.50
Melting point (Kelvin)
347.70
Boiling point (Celsius)
277.50
Boiling point (Kelvin)
550.60
General information
Molecular weight
162.03g/mol
Molar mass
162.0290g/mol
Density
1.4350g/cm3
Appearence

3,4-Dichloroaniline typically appears as a brown to tan solid crystalline powder. It may also present as colorless in its pure form. It is known for being a chlorinated derivative of aniline.

Comment on solubility

Solubility of 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline

The solubility of the compound 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline can be quite intriguing. This compound exhibits varying solubility characteristics depending on the solvent used, which is influenced by its functional groups and molecular structure. Here are some key observations regarding its solubility:

  • In water: This compound is generally poorly soluble. The presence of multiple chlorine atoms may enhance hydrophobic interactions, thus limiting its ability to dissolve in polar solvents like water.
  • In organic solvents: It tends to show better solubility in non-polar to moderately polar organic solvents, such as ethanol and acetone, where it can engage in van der Waals interactions.
  • Influencing factors: Factors affecting solubility include:
    • The presence of functional groups that can form hydrogen bonds or participate in dipole-dipole interactions.
    • The overall molecular weight and size, impacting how the compound interacts with solvent molecules.
    • Temperature, which can enhance the solubility of some compounds in certain solvents.

In conclusion, while 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline shows limited solubility in water, its behavior in organic solvents can vary and opens avenues for further exploration in terms of practical applications and chemical utilization.

Interesting facts

Interesting Facts About 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline

The compound known as 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline, often referred to in scientific literature, is a fascinating molecule with unique characteristics. Here are some interesting facts that highlight its significance in various fields:

  • Medicinal Chemistry: This compound is part of a larger class of aromatic amines, which are often investigated for their potential pharmaceutical applications. Aromatic amines can exhibit a range of biological activities, making them valuable in drug development.
  • Dye Industry: Due to the presence of multiple chloro and amino groups, 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline may find applications in dye syntheses. The functional groups allow for varied interactions, which can lead to vibrant colors in textile manufacturing.
  • Environmental Concerns: Aromatic amines, including this compound, have raised concerns due to their potential toxicity. It is crucial to handle such compounds with care in laboratory and industrial settings to mitigate any adverse environmental impacts.
  • Research Applications: Ongoing studies often explore the reactivity of such compounds in various chemical reactions, emphasizing their role in synthetic organic chemistry. Researchers might use this compound as an intermediate in more complex synthesis.
  • Controversial Compounds: Certain derivatives of aromatic amines have been linked to carcinogenic properties, which sparks debate in the scientific community regarding their regulation and safety. Therefore, compounds like 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline are often at the center of discussions about public health and safety.

In summary, the compound 4-(4-amino-3-chloro-phenyl)-2-chloro-aniline embodies the dual nature of chemical compounds—offering both utility and challenges. As with many chemical structures, further investigation can uncover new applications or highlight necessary precautions, underscoring the ever-evolving landscape of chemical research.

Synonyms
3,3'-DICHLOROBENZIDINE
91-94-1
3,3'-Dichlorobiphenyl-4,4'-diamine
Dichlorobenzidine base
o,o'-Dichlorobenzidine
3,3'-Dichlorbenzidin
3,3'-Dichlorobenzidina
Curithane C126
RCRA waste number U073
3,3'-Dichloro-4,4'-biphenyldiamine
Benzidine, 3,3'-dichloro-
3,3'-Dichloro-4,4'-diaminobiphenyl
3,3'-Dichloro-p,p'-bianiline
Curithane C 126
3,3'-Dichlorobenzidine base
CCRIS 220
ortho,ortho'-Dichlorobenzidine
C.I. 23060
3,3'-Dichloro-4,4'-diaminodiphenyl
4,4'-Diamino-3,3'-dichlorobiphenyl
4,4'-Diamino-3,3'-dichlorodiphenyl
4-(4-amino-3-chlorophenyl)-2-chloroaniline
3,3'-Dichlorobenzidin
3,3'-Dichlorbenzidin [Czech]
NSC 154073
3,3'-Dichlorobenzidin [Czech]
HSDB 1632
3,3'-Dichlorobenzidina [Spanish]
Dichlorobenzidine, 3,3'-
EINECS 202-109-0
3,3'-Dichloro-4,4'-diamino(1,1-biphenyl)
3,3'-Dichloro-(1,1'-biphenyl)-4,4'-diamine
3,3'-Dichloro-[1,1'-biphenyl]-4,4'-diamine
BRN 2108022
1SDI2328UX
CI 23060
DTXSID6020432
(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dichloro-
[1,1'-Biphenyl]-4,4'-diamine, 3,3'-dichloro-
NSC-154073
4'-Amino-3,3'-dichloro(1,1'-biphenyl)-4-ylamine
DTXCID60432
CHEBI:82315
NSC154073
3,3'-DICHLOROBENZIDINE [MI]
3,3'-DICHLOROBENZIDINE [HSDB]
3,3'-DICHLOROBENZIDINE [IARC]
3,3'-dichlorobiphenyl-4,4'-ylenediamine
86349-58-8
3,3'-Dichlorbenzidin (Czech)
3,3'-Dichlorobenzidina (Spanish)
3,3'-DICHLOROBENZIDIN (CZECH)
3,3'-DICHLOROBENZIDINE (IARC)
3,3-Dichloro-(1,1)-biphenyl-4,4-diamine
3,3-Dichloro-[1,1]-biphenyl-4,4-diamine
3,3 Dichlorobenzidine
3,3'-dichloro(1,1'-biphenyl)-4,4'-diamine
3,3'-Dichloro[1,1'-biphenyl]-4,4'-diamine
3,3' Dichlorobenzidine
4'-Amino-3,3'-dichloro[1,1'-biphenyl]-4-ylamine
3,3/'-Dichlorobenzidine
RCRA waste no. U073
UNII-1SDI2328UX
3,3'Dichlorbenzidin
o,o'Dichlorobenzidine
3,4'-diamine
3,3'Dichlorobenzidin
3,3'Dichlorobenzidina
4,3'-dichlorobiphenyl
4,3'-dichlorodiphenyl
3,3'-Diclorobencidina
Benzidine,3'-dichloro-
3,3'-dichloro-benzidine
3, 3'-Dichlorobenzidine
Benzidine, 3,3'dichloro
3,3'Dichlorobenzidine base
3,3'Dichlorop,p'bianiline
4-(4-amino-3-chloro-phenyl)-2-chloro-aniline
ortho,ortho'Dichlorobenzidine
SCHEMBL49382
WLN: ZR BG DR DZ CG
CHEMBL314470
3,3-Dichlorobenzidine-13C12
HUWXDEQWWKGHRV-UHFFFAOYSA-
3,3'-Dichlorobenzidine (OSHA)
3,3'-Diclorobencidina (Spanish)
3,3'Dichloro4,4'biphenyldiamine
3,3'Dichloro4,4'diaminobiphenyl
3,3'Dichloro4,4'diaminodiphenyl
3,3'Dichlorobiphenyl4,4'diamine
4,4'Diamino3,3'dichlorobiphenyl
4,4'Diamino3,3'dichlorodiphenyl
3,3'-Dichlorobenzidine (ACGIH)
ALBB-014126
MEA63082
Tox21_202224
[1,4'-diamine, 3,3'-dichloro-
3,3'-dichlor-4,4'-diaminobiphenyl
BBL034702
MFCD00043917
STL426665
4,4'Ddiamino-3,3'-dichlorobiphenyl
(1,1'-Biphenyl)-4,4'-diamine, 3,3'-dichloro-, labeled with carbon-14
AKOS005174428
3,3'-Dichloro-4, 4'-diaminodiphenyl
CAS-91-94-1
3,3'Dichloro4,4'diamino(1,1biphenyl)
NCGC00090883-03
NCGC00090883-04
NCGC00090883-05
NCGC00259773-01
FD123359
FD182138
VS-12642
3,3'Dichloro(1,1'biphenyl)4,4'diamine
DB-057279
(1,1'Biphenyl)4,4'diamine, 3,3'dichloro
4'Amino3,3'dichloro(1,1'biphenyl)4ylamine
NS00008259
3,3'-Dichloro-1,1'-biphenyl-4,4'-diamine
3,3-Dichloro-(1,1-Biphenyl)-4,4-Diamine
C19225
H30611
3,3 inverted exclamation marka-Dichlorobenzidine
Q222991
3,3'-Dichlorobenzidine 10 microg/mL in Acetonitrile
4'-Amino-3,3'-dichloro[1,1'-biphenyl]-4-ylamine #
3,3 inverted exclamation marka-dichloro-4,4 inverted exclamation marka-diaminobiphenyl
3,3'-Dichloro-[1,1'-biphenyl]-4,4'-diamine;3,3'-Dichlorobiphenyl-4,4'-diamine
202-109-0
InChI=1/C12H10Cl2N2/c13-9-5-7(1-3-11(9)15)8-2-4-12(16)10(14)6-8/h1-6H,15-16H2