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4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline

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Identification
Molecular formula
C13H12F2N2
CAS number
204931-97-5
IUPAC name
4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline
State
State

At room temperature, this compound is typically a solid.

Melting point (Celsius)
128.00
Melting point (Kelvin)
401.15
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.15
General information
Molecular weight
248.27g/mol
Molar mass
248.2660g/mol
Density
1.2970g/cm3
Appearence

This compound typically appears as a pale yellow to beige solid. The exact shade and texture can vary based on the specific sample and any impurities it might contain.

Comment on solubility

Solubility of 4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline

The solubility of the compound 4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline can be quite complex, primarily due to its functional groups and molecular structure. Here are some key points to consider:

  • Polar Characteristics: The presence of amino groups (-NH2) and fluorine atoms contributes to its overall polarity, which may enhance solubility in polar solvents like water.
  • Solvent Interaction: This compound is likely to exhibit better solubility in organic solvents, particularly those that can engage in hydrogen bonding or have polar characteristics.
  • Temperature Dependence: Solubility can be affected by temperature, with increased temperatures often leading to higher solubility rates for organic compounds.
  • pH Influence: The solubility could also vary with pH, as the amino group can become protonated in acidic conditions, potentially increasing the overall solubility in aqueous environments.

In summary, while the solubility of 4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline in water may not be remarkably high, it likely finds better solubility in polar organic solvents, showcasing a typical trend for amine-containing compounds.

Interesting facts

Interesting Facts about 4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline

4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline is a fascinating compound with notable properties and applications in various fields of chemistry. This compound is part of the aniline family, which is renowned for its role in the synthesis of dyes, rubber chemicals, and pharmaceuticals.

Key Characteristics:

  • Pharmaceutical Potential: The presence of the amino group in this compound provides opportunities for enhancing biological activity, making it valuable in medicinal chemistry.
  • Fluorine Atoms: The two fluorine substituents are known to influence the electronic properties of the molecule, leading to enhanced stability and reactivity.
  • Synthesis Use: This compound can serve as an essential intermediate in the synthesis of more complex organic molecules, demonstrating its importance in organic synthesis.

Applications:

  • Dyes and Pigments: It can be used in the manufacturing of vibrant dyes due to its chromophoric characteristics.
  • Research: This compound is often used in studies exploring the interactions between different molecular systems, contributing to a better understanding of chemical reactivity and bonding.

As one researcher aptly put it: "The integration of fluorine into organic compounds can unlock new avenues for discovery, highlighting the pivotal role of these halogens in modern chemistry." The study of 4-[(4-amino-3-fluoro-phenyl)methyl]-2-fluoro-aniline not only showcases the beauty of structural variety in organic molecules but also emphasizes the innovative potential waiting to be realized in the world of chemical compounds.

Synonyms
ANILINE, 4,4'-METHYLENEBIS(o-FLUORO-
4,4'-Methylenebis(o-fluoroaniline)
BRN 2735971
4,4'-Methylenebis(2-fluorobenzenamine)
Benzenamine, 4,4'-methylenebis(2-fluoro-
DTXSID40160551
Benzenamine, 4,4'-methylenebis[2-fluoro-
4,4'-Methylenebis[2-fluorobenzenamine]
DTXCID0083042
Benzenamine, 4,4'-methylenebis(2-fluoro-(9CI)
13824-23-2
4-[(4-amino-3-fluorophenyl)methyl]-2-fluoroaniline
MOFA
SCHEMBL864771