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Drotaverine Hydrochloride

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Identification
Molecular formula
C24H32ClNO4
CAS number
985-12-6
IUPAC name
4-(4-aminobenzoyl)oxybutyl-diethyl-ammonium;chloride
State
State

At room temperature, drotaverine hydrochloride exists as a solid.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.00
Boiling point (Celsius)
318.70
Boiling point (Kelvin)
591.70
General information
Molecular weight
397.94g/mol
Molar mass
397.9400g/mol
Density
1.1640g/cm3
Appearence

Drotaverine hydrochloride generally appears as a yellow crystalline powder. It may become unstable when exposed to light, usually requiring storage in a dark, dry environment.

Comment on solubility

Solubility of 4-(4-aminobenzoyl)oxybutyl-diethyl-ammonium chloride

The solubility of 4-(4-aminobenzoyl)oxybutyl-diethyl-ammonium chloride can be characterized by several key factors:

  • Polarity: This compound is quaternary ammonium salt, which typically enhances its solubility in polar solvents like water due to ion-dipole interactions.
  • Hydrophobic and Hydrophilic Balance: The presence of hydrophilic amine and chloride groups promotes solubility, while hydrophobic butyl and phenyl rings may introduce some limitations.
  • Temperature Dependency: Its solubility may increase with temperature due to greater kinetic energy facilitating the dissolution process.
  • Concentration Effects: Higher concentrations can lead to decreased solubility because of possible precipitation or the formation of aggregates.

In general, quaternary ammonium compounds like this one are known for their relatively good solubility in water, but the exact solubility will depend on specific conditions, such as pH and the presence of other ions in the solution. As a result, experimentation is often necessary to determine the precise solubility in a given solvent under varying conditions.

Interesting facts

Interesting Facts about 4-(4-Aminobenzoyl)oxybutyl-diethyl-ammonium Chloride

4-(4-Aminobenzoyl)oxybutyl-diethyl-ammonium chloride is a fascinating compound with unique properties and applications in various fields. This organic compound contains both amine and ammonium functional groups, making it an important molecule in medicinal and pharmaceutical chemistry.

  • Versatile Applications: One of the most notable uses of this compound is in drug delivery systems. Its ammonium structure allows it to interact effectively with biological membranes, enhancing the efficiency of targeted drug delivery.
  • Role in Biomedical Research: Researchers are investigating its potential in cancer treatments and therapeutics due to its ability to deliver active pharmaceutical ingredients directly to tumor sites.
  • Surface Activity: The presence of the diethylammonium group suggests surfactant-like properties. Such characteristics can improve the solubility of drugs and enhance their absorption in the body.
  • Structure-Function Relationship: The specific arrangement of the aromatic amine and ether functional groups plays a crucial role in its biological activity. Scientists are continuously studying these interactions to optimize drug design.
  • Environmental Considerations: Like many ammonium compounds, it is important to consider the environmental impact of this compound. Understanding its degradation pathways is crucial for its safe application in pharmaceutical processes.

In conclusion, the compound 4-(4-aminobenzoyl)oxybutyl-diethyl-ammonium chloride exemplifies the intersection of organic chemistry and pharmacology. Its unique functional groups and potential applications continue to pique the interest of researchers aiming to innovate safe and effective drug delivery methods for various diseases.

Synonyms
p-Aminobenzoic acid 4-(diethylamino)butyl ester hydrochloride
17599-20-1
BENZOIC ACID, p-AMINO-, 4-(DIETHYLAMINO)BUTYL ESTER, HYDROCHLORIDE