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Aspartame

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Identification
Molecular formula
C14H18N2O5
CAS number
22839-47-0
IUPAC name
4-(4-aminocyclohexa-2,5-dien-1-yl)-2-[[3-methyl-2-(methylamino)pentanoyl]amino]butanoic acid
State
State

Aspartame is typically found in a solid state at room temperature.

Melting point (Celsius)
246.00
Melting point (Kelvin)
519.15
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
294.31g/mol
Molar mass
294.3060g/mol
Density
1.3470g/cm3
Appearence

Aspartame is a white, odorless crystalline powder. It is often used as a sugar substitute in a variety of foods and beverages due to its intense sweetness.

Comment on solubility

Solubility of 4-(4-aminocyclohexa-2,5-dien-1-yl)-2-[[3-methyl-2-(methylamino)pentanoyl]amino]butanoic acid

The solubility of the compound 4-(4-aminocyclohexa-2,5-dien-1-yl)-2-[[3-methyl-2-(methylamino)pentanoyl]amino]butanoic acid can be influenced by various factors. Here are some key points to consider:

  • Polarity: The presence of polar groups in the structure suggests that this compound may have limited solubility in non-polar solvents and might be more soluble in polar solvents like water or alcohols.
  • Functional Groups: Functional groups such as amino and carboxylic acid may enhance solubility in aqueous solutions due to their ability to form hydrogen bonds.
  • pH Dependency: The solubility could vary significantly with changes in pH, as the amino and carboxyl groups can become protonated or deprotonated, affecting overall solubility.
  • Temperature Effects: Increased temperature often leads to increased solubility but must be evaluated experimentally to confirm this for specific compounds.

In general, solubility is a complex interplay of molecular structure and environmental conditions. As Stephen Hawking once said, "Intelligence is the ability to adapt to change," and in the realm of solubility, understanding how compounds respond to changing conditions is crucial for their practical application.

Interesting facts

Exploring the Unique Compound: 4-(4-aminocyclohexa-2,5-dien-1-yl)-2-[[3-methyl-2-(methylamino)pentanoyl]amino]butanoic acid

This compound holds significant interest within the realm of organic and medicinal chemistry. Here are some captivating facts about it:

  • Complex Structure: The compound features a unique bicyclic structure that introduces a level of complexity often sought in drug development. The presence of a cyclohexadiene moiety is particularly noteworthy, as it often results in interesting electronic properties.
  • Biological Relevance: Compounds like this one are of interest due to their potential use in pharmaceuticals, specifically as therapeutic agents. The coupling of amino acid motifs hints at the potential for interactions with biological systems, possibly acting as enzyme inhibitors or receptor modulators.
  • Functional Groups: This compound is rich in functional groups, including amines and carboxylic acids. These groups play crucial roles in the reactivity and solubility within biological systems, broadening the applications for which this compound can be utilized.
  • Synthetic Pathways: The synthesis of compounds containing such intricate structures is often challenging, providing exciting opportunities for chemists to develop novel synthetic methodologies. This could involve the use of multi-step reactions, protection/deprotection strategies, and coupling reactions.
  • Research Opportunities: Given its structural characteristics, there is significant potential for research aimed at elucidating its mechanism of action and biological activities. Such studies can lead to new insights in fields ranging from medicinal chemistry to materials science.

In summary, 4-(4-aminocyclohexa-2,5-dien-1-yl)-2-[[3-methyl-2-(methylamino)pentanoyl]amino]butanoic acid serves as a rich topic for both academic inquiry and practical application, embodying the intersections between chemical structure, function, and synthesis.

Synonyms
Stravidin
21754-03-0
4-(4-aminocyclohexa-2,5-dien-1-yl)-2-((3-methyl-2-(methylamino)pentanoyl)amino)butanoic acid
4-(4-aminocyclohexa-2,5-dien-1-yl)-2-[[3-methyl-2-(methylamino)pentanoyl]amino]butanoic acid
RefChem:185828
Stravidin-S3
Antibiotic msd-235-S3
MSD-235-S3
SCHEMBL29381646
DTXSID30944362
ATAHFPOIIFBWFN-UHFFFAOYSA-N
2,5-Cyclohexadiene-1-butyric acid, 4-amino-alpha-(3-methyl-2-(methylamino)valeramido)-
4-(4-Amino-2,5-cyclohexadienyl)-2-(2-(methylamino)-3-methylvaleramido)butyric acid
Butanoic acid, N-methyl-L-isoleucyl-4-(4-amino-2,5-cyclohexadien-1-yl)-L-amino-, trans-
Butyric acid, 4-(4-amino-2,5-cyclohexadienyl)-2-(2-(methylamino)-3-methylvaleramido)-
Butanoic acid, N-methyl-L-isoleucyl-gamma-(4-amino-2,5-cyclohexadien-1-yl)-L-alpha-amino-, (E)
4-(4-Aminocyclohexa-2,5-dien-1-yl)-2-{[1-hydroxy-3-methyl-2-(methylamino)pentylidene]amino}butanoic acid