Skip to main content

Bicuculline

ADVERTISEMENT
Identification
Molecular formula
C13H17N2
CAS number
485-49-4
IUPAC name
4-[(4-aminocyclohexyl)methyl]cyclohexanamine
State
State

At room temperature, Bicuculline is in a solid state. It is commonly encountered as a solid compound that is stable under normal conditions and used in research applications.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
213.34g/mol
Molar mass
213.3420g/mol
Density
1.0200g/cm3
Appearence

Bicuculline is typically found as a white crystalline solid. It may appear as a powder when synthesized and stored for laboratory use. It is often used in research settings where its detailed physical characteristics are relevant for handling and experimental protocols.

Comment on solubility

Solubility of 4-[(4-aminocyclohexyl)methyl]cyclohexanamine

When considering the solubility of 4-[(4-aminocyclohexyl)methyl]cyclohexanamine, several key factors come into play. The compound possesses both hydrophobic and hydrophilic characteristics, which can significantly influence its solubility in various solvents. Here are a few important points:

  • Polarity: Due to the presence of amine groups, the compound exhibits polar characteristics, enhancing its solubility in polar solvents such as water.
  • Hydrophobic Effects: The cyclohexane rings contribute to the hydrophobic nature of the compound, possibly reducing solubility in highly polar solvents.
  • Solvent Interaction: It may demonstrate better solubility in organic solvents like ethanol or methanol that can stabilize the structure through hydrogen bonding.

In general, the solubility of 4-[(4-aminocyclohexyl)methyl]cyclohexanamine is influenced by:

  1. Temperature: Higher temperatures may enhance solubility due to increased molecular motion.
  2. pH Level: The solubility may vary with pH, especially due to the ionization of the amine groups.

In conclusion, while the multiple functional groups in 4-[(4-aminocyclohexyl)methyl]cyclohexanamine suggest a favorable solubility in various solvents, the overall solubility will ultimately depend on the specific conditions of use.

Interesting facts

Interesting Facts About 4-[(4-Aminocyclohexyl)methyl]cyclohexanamine

4-[(4-aminocyclohexyl)methyl]cyclohexanamine, often referred to in scientific contexts by its slightly simpler abbreviation or by its IUPAC name, is an intriguing organic compound with several noteworthy aspects:

  • Structural Significance: This compound features a cyclohexane ring structure, which is noted for its unique ability to provide stability and rigidity to molecules. Cyclohexane derivatives, like this one, often exhibit interesting interactions with biological systems.
  • Functional Groups: The presence of amino groups (-NH₂) in its structure makes it an amine, which opens up avenues for interaction with various biological molecules. Amines can act as bases, forming salts that may be of interest in pharmaceutical applications.
  • Potential Applications: Given the structural complexities and the reactivity of 4-[(4-aminocyclohexyl)methyl]cyclohexanamine, it has potential implications in medicinal chemistry. Compounds of this nature could serve as precursors in the synthesis of drugs or as intermediates in various chemical reactions.
  • Research Interest: Scientists are exploring the effects of cyclohexylamine compounds on neurotransmitter systems. The compound’s unique bonding characteristics help researchers better understand its effects on the central nervous system.
  • Environmental Impact: Like many amines, this compound is also being studied for its environmental breakdown. The biodegradation pathways of such organic compounds are essential for understanding their long-term ecological impact.

As a fascinating component of organic synthesis, 4-[(4-aminocyclohexyl)methyl]cyclohexanamine continues to capture the attention of chemists seeking to unlock its full potential through research and application in various fields, particularly in pharmaceuticals.

Synonyms
1761-71-3
4,4'-Diaminodicyclohexylmethane
4,4'-Methylenebis(cyclohexylamine)
Wandamin HM
4,4'-Diaminodicyclohexyl methane
Cyclohexanamine, 4,4'-methylenebis-
AR21XLU05L
B16001JGEW
H8V09V2RM3
DTXSID0024921
Cyclohexanamine, 4,4'-methylenebis-, (cis,trans)-
Cyclohexanamine, 4,4'-methylenebis-, (trans,trans)-
4,4'-Methylenebiscyclohexanamine, (cis,cis)-
4,4'-Methylenebis(aminocyclohexane)
EINECS 229-737-8
EINECS 229-738-3
EINECS 229-739-9
4,4'-Methylenebiscyclohexanamine, (cis,trans)-
4,4'-Methylenebiscyclohexanamine, (trans,trans)-
Cyclohexanamine, 4,4'-methylenebis-, (cis,cis)-
DTXCID204921
0NW77H1O03
Cyclohexanamine, 4,4'-methylenebis-, (cis(cis))-
Cyclohexanamine, 4,4'-methylenebis-, [cis(cis)]-
Di(paminocyclohexyl)methane
Bis(paminocyclohexyl)methane
bis(4aminocyclohexyl)methane
p,p'Diaminodicyclohexylmethane
4,4'diaminodicyclohexylmethane
4,4'Methylenedicyclohexanamine
4,4'Methylenedicyclohexylamine
1,4Bis(aminocyclohexyl)methane
Methylenebis(4aminocyclohexane)
4,4'Methylenedicyclohexaneamine
methylenebis(4-cyclohexylamine)
4,4'-methylenebiscyclohexanamine
4,4'Methylenebis(cyclohexanamine)
Cyclohexanamine, 4,4'methylenebis
Cyclohexylamine, 4,4'methylenebis
DIAMINODICYCLOHEXYLMETHANE, 4,4'-
CYCLOHEXYLAMINE, 4,4-METHYLENEBIS-
4-(4-AMINOCYCLOHEXYLMETHYL)CYCLOHEXANAMINE
S 509361
4-(4-AMINOCYCLOHEXYLMETHYL)-1-CYCLOHEXYLAMINE
217-168-8
4,4'-Methylenedicyclohexanamine
Bis(4-aminocyclohexyl)methane
4,4-diaminodicyclohexyl methane
6693-29-4
6693-31-8
Bis(p-aminocyclohexyl)methane
4-[(4-aminocyclohexyl)methyl]cyclohexan-1-amine
HLR 4219
PACM 20
Cyclohexylamine, 4,4'-methylenebis-
p,p'-Diaminodicyclohexylmethane
4,4'-Methylenedicyclohexylamine
6693-30-7
Methylenebis(4-aminocyclohexane)
4,4'-Methylenedicyclohexaneamine
4,4'-Methylenebis(cyclohexanamine)
DI(P-AMINOCYCLOHEXYL)METHANE
HLR 4448
[Cis(cis)]-4,4'-methylenebis(cyclohexylamine)
[Trans(cis)]-4,4'-methylenebis(cyclohexylamine)
[trans(trans)]-4,4'-methylenebis(cyclohexylamine)
1,4-Bis(aminocyclohexyl)methane
4,4'-methylenebiscyclohexylamine
CCRIS 4777
(cis(cis))-4,4'-Methylenebis(cyclohexylamine)
(trans(cis))-4,4'-Methylenebis(cyclohexylamine)
(trans(trans))-4,4'-Methylenebis(cyclohexylamine)
EINECS 217-168-8
UNII-AR21XLU05L
BRN 2079179
UNII-B16001JGEW
UNII-H8V09V2RM3
UNII-0NW77H1O03
4,4-Methylenebiscyclohexylamine
4,4'-diamino dicyclohexylmethane
MFCD00001496
EC 217-168-8
SCHEMBL16270
bis (4-aminocyclohexyl)methane
SCHEMBL1201897
SCHEMBL1923266
SCHEMBL7957715
SCHEMBL7960126
SCHEMBL9496945
CHEMBL1492978
SCHEMBL14345766
SCHEMBL16803282
SCHEMBL16803386
SCHEMBL18808443
SCHEMBL21277472
DTXSID00891273
DTXSID40891277
DTXSID80891276
4,4'-Bis(aminocyclohexyl)methane
bis-(4-amino-cyclohexyl)-methane
(4,4'-Diaminodicyclohexyl)methane
4,4\'-Diaminodicyclohexyl methane
Tox21_200300
AKOS000120245
NCGC00091667-01
NCGC00091667-02
NCGC00091667-03
NCGC00257854-01
AC-20547
BS-42195
4,4'-Methylenebis(cyclohexylamine), 97%
CAS-1761-71-3
(cis,cis)-4,4'-methylenebiscyclohexanamine
CS-0077153
M0699
NS00002394
(cis,trans)-4,4'-methylenebiscyclohexanamine
EN300-20431
(trans,trans)-4,4'-methylenebiscyclohexanamine
4-[(4-Aminocyclohexyl)methyl]cyclohexylamine #
E77206
(cis,cis)-4,4a(2)-Methylenebis[cyclohexanamine]
(trans,trans)-4,4'-Methylenebis[cyclohexanamine]
(cis,trans)-4,4a(2)-Methylenebis[cyclohexanamine]
Q16736630
Q27274069
Q27274239
Q27279773
4,4'-Methylenebis(cyclohexylamine), technical grade, 95%
(cis,cis)-4,4invertedexclamationmarka-Methylenebis[cyclohexanamine]
4,4'-Methylenebis(cyclohexylamine) 100 microg/mL in Acetonitrile
(cis,cis)-4,4 inverted exclamation marka-Methylenebis[cyclohexanamine]
(cis,trans)-4,4 inverted exclamation marka-Methylenebis[cyclohexanamine]
(trans,trans)-4,4 inverted exclamation marka-Methylenebis[cyclohexanamine]