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Gabapentin

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Identification
Molecular formula
C9H11NO2
CAS number
60142-96-3
IUPAC name
4-(4-aminophenyl)butanoic acid
State
State

Gabapentin is typically found as a solid powder at room temperature.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.20
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
171.24g/mol
Molar mass
171.2370g/mol
Density
1.2000g/cm3
Appearence

Gabapentin appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-(4-aminophenyl)butanoic acid

4-(4-aminophenyl)butanoic acid, also known as a derivative of amino acids, exhibits unique solubility characteristics influenced by its chemical structure. Understanding its solubility can be summarized as follows:

  • Polar Nature: The presence of a carboxylic acid group (–COOH) contributes significantly to its polar character, enhancing solubility in polar solvents like water.
  • Effect of Amino Group: The amino (-NH2) group can form hydrogen bonds, further aiding in solubility in a variety of aqueous solutions.
  • Hydrophobic Portion: Despite its polar features, the aromatic phenyl group adds a hydrophobic character that can reduce solubility in non-polar solvents.
  • pH Dependency: The solubility of 4-(4-aminophenyl)butanoic acid can be pH-dependent, as the ionization of the carboxyl group varies in different pH environments.

To summarize, the overall solubility of 4-(4-aminophenyl)butanoic acid is significantly enhanced in polar solvents and may vary based on factors such as pH and temperature. Understanding these aspects is essential for applications in fields such as pharmaceuticals and biochemical research.

Interesting facts

Interesting Facts about 4-(4-Aminophenyl)butanoic Acid

4-(4-Aminophenyl)butanoic acid, often abbreviated as 4-ABPA, is a notable compound in the realm of organic chemistry with a variety of fascinating aspects:

  • Structural Importance: The compound features an aromatic amine structure, which is significant due to its potential biological activities.
  • Medicinal Applications: Compounds like 4-ABPA are investigated for their pharmacological properties, particularly in the development of drugs targeting various diseases.
  • Research Utilization: It serves as a useful intermediate in the synthesis of more complex molecules in materials science and medicinal chemistry.
  • Amine Functionality: The presence of the amino group in its structure offers opportunities for further chemical modifications, making it a versatile building block for synthesizing other compounds.

Furthermore, the exploration of 4-ABPA in chemical research reflects wider trends in the advancement of pharmaceutical sciences, highlighting the balance between structure and function in drug design. As chemists continue to unravel the interactions of amine groups with biological systems, compounds like 4-(4-aminophenyl)butanoic acid are likely to remain at the forefront of research.

To sum it up, this compound exemplifies the rich interplay between chemistry and biology, showcasing how a seemingly simple structure can lead to significant scientific breakthroughs.

Synonyms
4-(4-aminophenyl)butanoic acid
628-142-4
4-(4-Aminophenyl)butyric acid
15118-60-2
Benzenebutanoic acid, 4-amino-
MFCD00075052
4-(P-AMINOPHENYL)BUTYRIC ACID
4-(4-Aminophenyl)butyricacid
4-(p-Aminophenyl)butyric Acid; 4-Aminobenzenebutanoic Acid; NSC 27531
NSC27531
4-aminobenzenebutanoic acid
4(4-aminophenyl)butyric acid
4-(4aminophenyl)butyric acid
SCHEMBL434792
CHEMBL1650245
4 -(4-aminophenyl)butyric acid
4-(4-amino-phenyl)butyric acid
4-(4-aminophenyl) butyric acid
4-(4-aminophenyl)-butyric acid
DTXSID50164727
RBHLFWNKEWLHBP-UHFFFAOYSA-N
4-(4-amino-phenyl)-butyric acid
NSC 27531
NSC-27531
AKOS004117887
4-(4-Aminophenyl)butyric acid, 95%
CCG-301696
CS-W017265
DS-12283
SY101993
DB-006538
ST51038186
EN300-108862
Z336079594
915232-04-1