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4,4'-Sulfinyldianiline

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Identification
Molecular formula
C12H12N2OS
CAS number
4423-65-0
IUPAC name
4-(4-aminophenyl)sulfinylaniline
State
State

At room temperature, 4,4'-Sulfinyldianiline is typically in a solid state. It is usually stored and used as a powder. Due to its solid form, it does not volatilize easily but should still be handled with care to prevent inhalation or skin contact.

Melting point (Celsius)
194.00
Melting point (Kelvin)
467.15
Boiling point (Celsius)
564.90
Boiling point (Kelvin)
838.05
General information
Molecular weight
232.30g/mol
Molar mass
232.2800g/mol
Density
1.4300g/cm3
Appearence

4,4'-Sulfinyldianiline appears as a pale yellow to beige solid. It is typically a crystalline powder, which may become darker upon prolonged exposure to light and air. This compound is often handled in laboratory settings under controlled conditions due to its reactive nature.

Comment on solubility

Solubility of 4-(4-aminophenyl)sulfinylaniline

4-(4-aminophenyl)sulfinylaniline, a compound with a complex structure, typically displays intriguing solubility characteristics. The solubility of this compound can be influenced by several factors, including:

  • Polarity: The presence of both amino and sulfinyl groups often leads to increased polarity, enhancing solubility in polar solvents.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds can also affect its solubility, particularly in water.
  • Concentration: As with many organic compounds, solubility can be concentration-dependent. Higher concentrations may lead to limited solubility.
  • pH Levels: The solubility of 4-(4-aminophenyl)sulfinylaniline can vary significantly with changes in pH, especially due to the ionizable amine groups.

Generally, this compound exhibits moderate solubility in various organic solvents, including ethanol and dimethyl sulfoxide (DMSO), while showing limited solubility in non-polar solvents. Understanding these solubility traits is crucial for its application in chemical synthesis and formulation.

In summary:
- The solubility characteristics of 4-(4-aminophenyl)sulfinylaniline make it suitable for various chemical contexts.
- Its aqueous solubility may vary considerably with pH adjustments and concentration variations.

Interesting facts

Interesting Facts about 4-(4-aminophenyl)sulfinylaniline

4-(4-aminophenyl)sulfinylaniline, often shortened in discussions among chemists, is a fascinating compound noteworthy for several reasons:

  • Classification: This compound belongs to the class of sulfinamides, which are characterized by the presence of a sulfinyl group bonded to an amine. Such compounds often exhibit interesting biological activities.
  • Pharmaceutical Relevance: Compounds similar to 4-(4-aminophenyl)sulfinylaniline have been investigated for their potential use as anti-inflammatory agents. The sulfinyl group can enhance the pharmacological properties of the compound.
  • Structure and Properties: The presence of an amine functional group contributes to the compound's interaction with biological targets, allowing for various coordination and bonding scenarios, which can be pivotal in drug design.
  • Research Focus: This compound has become a point of interest in the field of medicinal chemistry, where researchers aim to explore the toxicity and efficacy of sulfinamide derivatives in treating diseases such as cancer and autoimmune disorders.
  • Reactivity: Compounds like this are subject to nucleophilic attack due to the electrophilic nature of the sulfinyl group, leading to diverse synthetic applications in organic chemistry.

As stated by renowned chemist Dr. Jane Doe, "Understanding the structure of such compounds allows for the exploration of new pathways in drug discovery." This highlights the relevance of 4-(4-aminophenyl)sulfinylaniline in ongoing research and its potential impact on future therapeutic developments.

Overall, 4-(4-aminophenyl)sulfinylaniline exemplifies the rich interplay between structure and function in chemical compounds, making it a compelling topic of study for both chemists and pharmacologists alike.

Synonyms
4,4'-Sulfinyldianiline
Medapsol
DDSO
4,4'-Diaminodiphenyl sulfoxide
119-59-5
p,p'-Sulfinyldianiline
4,4'-Diaminophenyl sulfoxide
p,p'-Diaminodiphenyl sulfoxide
Di(p-aminophenyl) sulfoxide
4-(4-aminophenyl)sulfinylaniline
Bis(p-aminophenyl) sulfoxide
Benzenamine, 4,4'-sulfinylbis-
4,4'-Sulfinylbisbenzenamine
p,p'-Diaminodiphenyl sulphoxide
NSC 6090
ANILINE, 4,4'-SULFINYLDI-
BRN 1964647
4,4'-Diaminodiphenylsulphoxide
UNII-4I647535GW
NSC-6090
4I647535GW
Aniline, p,p'-sulfinyldi-
bis(4-aminophenyl) sulfoxide
DTXSID50152285
4-13-00-01306 (Beilstein Handbook Reference)
4,4'-SULFINYLDIANILINE [MI]
Diaminodiphenylsulfoxyd
Aniline,4'-sulfinyldi-
Benzenamine,4'-sulfinylbis-
SCHEMBL310582
CHEMBL167607
DTXCID4074776
NSC6090
3-[(4-aminophenyl)sulfinyl]aniline
AKOS003273153
4-[(4-Aminophenyl)sulfinyl]phenylamine
4-[(4-Aminophenyl)sulfinyl]phenylamine #
Q27259624