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Fluoribiprofen

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Identification
Molecular formula
C14H20F2NO2
CAS number
182627-03-8
IUPAC name
4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid
State
State

At room temperature, Fluoribiprofen is in a solid state.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.20
Boiling point (Celsius)
576.20
Boiling point (Kelvin)
849.30
General information
Molecular weight
341.38g/mol
Molar mass
341.3760g/mol
Density
1.3070g/cm3
Appearence

Fluoribiprofen is a white to off-white crystalline powder. It is generally odorless and tasteless.

Comment on solubility

Solubility of 4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid

The solubility of 4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid can be quite intriguing due to its unique chemical structure. This compound contains both hydrophobic and hydrophilic regions, which can significantly influence its solubility behavior in various solvents.

Factors Affecting Solubility:

  • Polar vs. Nonpolar Solvents: Generally, compounds with polar functional groups tend to be more soluble in polar solvents (like water), while nonpolar regions promote solubility in nonpolar solvents (such as hexane).
  • Temperature: Increased temperature typically enhances solubility for many solids due to increased molecular motion.
  • pH Levels: As a carboxylic acid, the solubility of the compound may also depend on the pH of the solution; at higher pH, it may ionize, thus increasing its solubility in water.

In practical applications, it is suggested that this compound may exhibit limited solubility in aqueous media due to its bulky hydrophobic groups. Therefore, scientists and formulators might consider the use of organic solvents or surfactants to increase its effective solubility for various purposes.

As a key takeaway, understanding the solubility of 4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid is essential for effectively utilizing its properties in chemical and pharmaceutical contexts. Always remember: the principle of "like dissolves like" can provide valuable insights when predicting solubility behavior!

Interesting facts

Interesting Facts about 4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic Acid

4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid is a fascinating compound that falls within the realm of organic chemistry. Here are some insights that highlight its significance:

  • Pharmaceutical Applications: This compound is often studied within the field of medicinal chemistry due to its potential therapeutic applications. Compounds with similar structures have been explored for their roles as antitumor agents and in the treatment of various cancers.
  • Fluorinated Compounds: With the presence of fluorine in its structure, this compound showcases some unique properties that enhance its biological activity, stability, and lipophilicity. The incorporation of fluorine atoms can significantly influence the pharmacokinetics of drugs.
  • Research Insights: Studies indicate that compounds like this one can undergo significant metabolic transformations in the body. Researchers are particularly interested in how the bis(2-fluoroethyl)amino group affects these transformations.
  • Structure-Activity Relationship: The design of this compound allows chemists to explore the structure-activity relationship (SAR) extensively. By altering the chain lengths or functional groups, scientists can obtain insights into how these modifications impact the compound’s efficacy.

In summary, 4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid is not only a compound of interest for its potential medical implications but also serves as a vital tool in understanding how various chemical modifications affect biological properties. As research continues, the versatility of such compounds is likely to unfold even more captivating possibilities!

Synonyms
BUTYRIC ACID, 4-(p-(BIS(2-FLUOROETHYL)AMINO)PHENYL)-
4092-86-8
NSC 82835
BRN 2813842
4-(p-(Bis(2-fluoroethyl)amino)phenyl)butyric acid
DTXSID00193926
DTXCID40116417
HRQ576LM4R
NSC-82835
NSC82835
4-[4-[bis(2-fluoroethyl)amino]phenyl]butanoic acid
UNII-HRQ576LM4R
NCIOpen2_004532
4-[Bis(2-fluoroethyl)amino]benzenebutanoic acid
Benzenebutanoic acid, 4-[bis(2-fluoroethyl)amino]-