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nonidet CH497

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Identification
Molecular formula
C20H23ClN2O4
CAS number
41036-16-8
IUPAC name
[4-(4-chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
State
State

This compound is typically found in a solid state at room temperature. It exists primarily as a stable crystalline powder under standard conditions.

Melting point (Celsius)
204.50
Melting point (Kelvin)
477.65
Boiling point (Celsius)
540.50
Boiling point (Kelvin)
813.65
General information
Molecular weight
366.86g/mol
Molar mass
366.8560g/mol
Density
1.2275g/cm3
Appearence

The compound appears as a white solid powder. It is usually supplied as a crystalline powder, which may clump upon exposure to air. The color may slightly vary from pure white depending on sample purity and storage conditions.

Comment on solubility

Solubility of [4-(4-chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone

The solubility of the compound [4-(4-chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone in various solvents is an important aspect to consider for its practical applications. This compound, featuring a complex aromatic structure, presents various solubility characteristics:

  • Polar Solvents: Generally, this compound may have low solubility in polar solvents such as water due to the hydrophobic nature of the aromatic groups.
  • Non-Polar Solvents: It is more likely to exhibit higher solubility in non-polar or slightly polar organic solvents, such as dichloromethane or ethyl acetate, where similar hydrophobic interactions can facilitate dissolution.
  • pH Dependence: The solubility can vary with pH; adjusting the pH of the solution may enhance the compound's solubility by protonation and altering its ionization state.

In conclusion, the solubility of this compound will largely depend on the solvent's polarity and the specific interactions between the compound and the solvent molecules. Understanding these solubility dynamics is crucial for effective formulation and application of the compound in chemical processes.

Interesting facts

Interesting Facts about [4-(4-chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone

This compound is an intriguing member of the class of chemical entities known as piperazinyl derivatives. With its unique structure, it combines features that can influence both biological activity and potential therapeutic applications.

Key Features

  • Piperazine moiety: The presence of the piperazine ring is notable because it commonly appears in many pharmaceuticals, particularly in psychotropic drugs. This means it has a potential role in influencing neurotransmitter activity in the brain.
  • Trimethoxy group: The 3,4,5-trimethoxy substitution can enhance lipophilicity, possibly affecting the bioavailability and distribution of the compound within biological systems.
  • Chlorophenyl substituent: The 4-chlorophenyl group may contribute to the compound's pharmacological properties, as halogen substituents often fine-tune molecular interactions with biological targets.

As a chemist or a student in the field, you might appreciate the significance of such modifications:

  • This compound’s design showcases the classic *structure-activity relationship* principles, where alterations in the molecular framework can lead to significantly different biological outcomes.
  • It serves as a model for understanding how *molecular interactions* can be fine-tuned to optimize drug efficacy.

In summary, [4-(4-chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone represents a fascinating intersection of organic chemistry and pharmacology, highlighting the importance of molecular design in creating effective therapeutic agents. Its potential could pave the way for research into new treatments for various conditions, making it a compound of significant interest in the scientific community.

Synonyms
17766-66-4
BRN 1603839
KETONE, 4-(p-CHLOROPHENYL)PIPERAZINYL 3,4,5-TRIMETHOXYPHENYL
1-(p-Chlorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
4-(p-Chlorophenyl)piperazinyl 3,4,5-trimethyoxyphenyl ketone
Piperazine, 1-(p-chlorophenyl)-4-(3,4,5-trimethoxybenzoyl)-
DTXSID70170360
DTXCID2092851
5-23-01-00179 (Beilstein Handbook Reference)
4-(p-Chlorophenyl)-1-piperazinyl(3,4,5-trimethoxyphenyl) ketone
[4-(4-chlorophenyl)piperazin-1-yl]-(3,4,5-trimethoxyphenyl)methanone
STK443314
AKOS001424224
ST50780553
SR-01000594970
SR-01000594970-1
Z283696430
1-(4-chlorophenyl)-4-(3,4,5-trimethoxybenzoyl)piperazine
4-(4-chlorophenyl)piperazinyl 3,4,5-trimethoxyphenyl ketone
[4-(4-chlorophenyl)piperazin-1-yl](3,4,5-trimethoxyphenyl)methanone