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Curcumin

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Identification
Molecular formula
C21H20O6
CAS number
458-37-7
IUPAC name
4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one
State
State

At room temperature, curcumin is in a solid state, specifically a crystalline powder.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
593.00
Boiling point (Kelvin)
866.15
General information
Molecular weight
368.39g/mol
Molar mass
368.3850g/mol
Density
1.4150g/cm3
Appearence

Curcumin appears as a bright yellow to orange crystalline powder. It is naturally occurring and primarily responsible for the yellow color of turmeric. It has a distinctive spicy aroma and taste.

Comment on solubility

Solubility of 4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one

The compound 4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one, commonly known as a type of chalcone, exhibits interesting solubility characteristics that are influenced by its molecular structure and functional groups.

Generally, the solubility of this compound can be discussed in the following terms:

  • Polarity: The presence of hydroxyl (-OH) and methoxy (-OCH3) functional groups suggests a degree of polarity, which can enhance solubility in polar solvents like water to some extent.
  • Solvent Compatibility: This compound is likely to be more soluble in organic solvents such as ethanol, methanol, and acetone due to its hydrophobic aromatic rings.
  • Temperature Influence: Solubility may increase with temperature; as the kinetic energy of molecules rises, solvation processes may be more efficient.
  • Concentration Effects: Like many organic compounds, solubility can also be affected by the concentration of the solution, where higher concentrations may lead to lower relative solubility due to saturation.

In conclusion, 4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one showcases moderate solubility in polar and non-polar solvents, driven by its unique functional groups and molecular interactions. However, for precise solubility data and applications, it is recommended to conduct empirical measurements in a laboratory setting.

Interesting facts

Interesting Facts about 4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one

This compound, commonly known in the field of organic chemistry as a derivative of curcumin, showcases fascinating properties that make it a subject of study for both its biochemical and industrial applications. Here are some engaging insights:

  • Natural Inspirations: This compound is inspired by the natural phenolic compounds found in turmeric, which has been used for centuries in both culinary practices and traditional medicine.
  • Bioactivity: Studies have shown that this compound exhibits notable anti-inflammatory and antioxidant properties. Curcumin analogs, like this one, are often explored for their potential therapeutic effects against various diseases.
  • Research Applications: Researchers are continually investigating its effects on chronic conditions, including cancer and neurodegenerative diseases. Its ability to modulate various signaling pathways makes it a valuable candidate in drug development.
  • Chemical Versatility: The structure of the compound allows for various chemical modifications, which can further enhance its efficacy and bioavailability. This characteristic is particularly important in medicinal chemistry.
  • Synthetic Pathways: The synthesis of this compound involves a series of chemical reactions that can teach students about important organic synthesis techniques, such as aldol condensation and nucleophilic addition.

In conclusion, 4-(4-hydroxy-3-methoxy-phenyl)but-3-en-2-one is not just a compound of interest from a chemical perspective but also a promising candidate in the fields of pharmacology and biotechnology. Its diverse properties and potential applications make it a thrilling subject for ongoing research and exploration!

Synonyms
3-Buten-2-one, 4-(4-hydroxy-3-methoxyphenyl)-, (3E)-
AFWKBSMFXWNGRE-UHFFFAOYSA-N
SY040651
SY234841
DB-040801
NS00021498
1-(4-Hydroxy-3-methoxyphenyl)-1-buten-3-one
1-(3'-methoxy-4'-hydroxyphenyl)-1-butene-3-one
1-(4'-hydroxy-3'-methoxyphenyl)-1-butene-3-one
4-(4'-hydroxy-3'-methoxyphenyl)-3-buten-2-one
4-(4-hydroxy-3-methoxy-phenyl)but-3-ene-2-one