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4-[(4-nitrophenyl)methyl]pyridine

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Identification
Molecular formula
C12H10N2O2
CAS number
13349-82-1
IUPAC name
4-[(4-nitrophenyl)methyl]pyridine
State
State

At room temperature, 4-[(4-nitrophenyl)methyl]pyridine is a solid compound. It tends to be stable under normal conditions of temperature and pressure.

Melting point (Celsius)
109.00
Melting point (Kelvin)
382.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
214.22g/mol
Molar mass
214.2180g/mol
Density
1.2350g/cm3
Appearence

4-[(4-nitrophenyl)methyl]pyridine appears as a crystalline solid. The compound typically exhibits a yellow color, owing to the presence of the nitro group in the structure. The crystals are often in the shape of fine powders or small granules.

Comment on solubility

Solubility of 4-[(4-nitrophenyl)methyl]pyridine

The solubility of 4-[(4-nitrophenyl)methyl]pyridine is influenced by several factors due to its distinct molecular structure. Here are some key points to consider:

  • Polarity: The presence of the pyridine ring and nitro group contributes to its overall polarity, which can affect its interactions with solvents.
  • Solvent Type: This compound tends to be more soluble in polar solvents such as water and ethanol compared to non-polar solvents.
  • Concentration: Solubility can vary significantly with concentration and temperature, so it is essential to evaluate these conditions experimentally.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvents can enhance solubility in polar environments.

To sum it up, it is often stated that compounds like 4-[(4-nitrophenyl)methyl]pyridine, with polar characteristics, exhibit higher solubility in polar solvents. The importance of these factors cannot be overstated when attempting to predict or utilize solubility in practical applications.

Interesting facts

Interesting Facts about 4-[(4-Nitrophenyl)methyl]pyridine

4-[(4-Nitrophenyl)methyl]pyridine is a fascinating compound that belongs to the family of pyridines, which are known for their diverse applications in various fields, including medicinal chemistry, agrochemicals, and material science. Here are some interesting insights:

  • Biological Activity: This compound exhibits intriguing biological properties, making it a potential candidate for pharmacological research. In particular, it has been studied for its role in developing novel drugs targeting specific biological pathways.
  • Industrial Applications: 4-[(4-Nitrophenyl)methyl]pyridine serves as an intermediate in the synthesis of several organic compounds. Its versatility allows for multiple pathways in complex chemical syntheses, essential in the production of various agrochemicals and dyes.
  • Electron-withdrawing Group: The nitro group in its structure plays a significant role in its reactivity and interaction with other compounds. As an electron-withdrawing group, it enhances the compound's nucleophilicity, impacting its position in synthetic pathways and reaction mechanisms.
  • Structural Diversity: The compound showcases how modifications on the pyridine ring can lead to structural diversity, which is crucial for tailoring properties suitable for specific applications, such as in the fields of organic electronics and sensor technology.
  • Environmentally Relevant: Studies have indicated that compounds like 4-[(4-Nitrophenyl)methyl]pyridine may have an environmental impact through their degradation products, prompting scientists to explore their ecological risks and toxicity.

In conclusion, 4-[(4-Nitrophenyl)methyl]pyridine not only serves as a valuable tool in synthetic organic chemistry but also illustrates the complex interplay between structure and functionality in chemical compounds. Its ongoing research reflects the broader trends in chemistry aimed at understanding and harnessing the properties of organic molecules for better, more sustainable applications.

Synonyms
4-(4-Nitrobenzyl)pyridine
1083-48-3
4-[(4-nitrophenyl)methyl]pyridine
4-(p-Nitrobenzyl)pyridine
Pyridine, 4-[(4-nitrophenyl)methyl]-
1-(p-Nitrobenzyl)pyridine
4-Nitrobenzylpyridine
PYRIDINE, 4-(p-NITROBENZYL)-
4(4-Nitrobenzyl)primide
gamma-(p-Nitrobenzyl)pyridine
NSC 83591
.gamma.-(p-Nitrobenzyl)pyridine
Pyridine, 4-((4-nitrophenyl)methyl)-
.gamma.-(4-Nitrobenzyl)pyridine
EINECS 214-108-2
UNII-0Z6GS37N7H
4-(4'-nitrobenzyl)pyridine
BRN 0170877
0Z6GS37N7H
NSC-83591
4-[4-Nitrobenzyl]pyridine
DTXSID2061482
5-20-07-00564 (Beilstein Handbook Reference)
PYRIDINE, 4-(P-NITROBENZYL)
4-((4-NITROPHENYL)METHYL)PYRIDINE
gamma-(4-Nitrobenzyl)pyridine
DTXCID6033110
214-108-2
inchi=1/c12h10n2o2/c15-14(16)12-3-1-10(2-4-12)9-11-5-7-13-8-6-11/h1-8h,9h
mnhkucbxxmfqdm-uhfffaoysa-n
MFCD00006445
MLS000711959
SMR000281726
4-(4-Nitro-benzyl)-pyridine
CBMicro_019234
Cambridge id 5373029
4-(4-Nitrobenzyl)-pyridin
NCIOpen2_004508
Oprea1_403743
cid_14129
SCHEMBL177812
CHEMBL1606980
BDBM94219
HMS2625J17
4-(4-Nitrobenzyl)pyridine, 98%
ALBB-032508
CCG-7579
NSC83591
STK396587
AKOS000446143
SB55064
NCGC00245125-01
SY070035
BIM-0019472.P001
DB-040826
EU-0066581
N0183
NS00015945
EN300-20019
A51036
11N-102
SR-01000596951
SR-01000596951-1
Q27251065
4-(4-Nitrobenzyl)pyridine, for TLC derivatization, for spectrophotometric det. of phosphorus-containing pesticides