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4-(4-nitrophenyl)morpholine

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Identification
Molecular formula
C10H12N2O3
CAS number
135-88-6
IUPAC name
4-(4-nitrophenyl)morpholine
State
State

At room temperature, 4-(4-nitrophenyl)morpholine is typically a solid. It is usually observed in parameter-controlled environments, such as laboratories, where it is handled with care due to its chemically reactive nature.

Melting point (Celsius)
81.00
Melting point (Kelvin)
354.15
Boiling point (Celsius)
327.00
Boiling point (Kelvin)
600.15
General information
Molecular weight
222.22g/mol
Molar mass
222.2210g/mol
Density
1.3412g/cm3
Appearence

4-(4-nitrophenyl)morpholine appears as a crystalline solid that varies from yellow to orange in color. The compound is typically well-formed into small crystal structures which can reflect light, giving it a shiny appearance. The intensity of the yellow hue may vary slightly depending on the purity and environmental factors.

Comment on solubility

Solubility of 4-(4-nitrophenyl)morpholine

The solubility of 4-(4-nitrophenyl)morpholine (C10H12N2O3) displays some intriguing characteristics. Its behavior in various solvents can significantly impact its application in different chemical processes.

In Solvent Solutions:

  • Polar Solvents: 4-(4-nitrophenyl)morpholine is expected to be soluble in polar solvents due to the presence of the morpholine ring, which exhibits basic properties.
  • Non-Polar Solvents: While it may show limited solubility in non-polar solvents because of its polar substituents, the overall structure allows for some interaction.
  • Aqueous Solutions: Its solubility in water is moderate, influenced by the balance of hydrophilic and hydrophobic characteristics.

It is interesting to note that the presence of the nitrophenyl group can also affect solubility behavior by introducing electron-withdrawing effects, thereby influencing intermolecular interactions.

In summary, the solubility of 4-(4-nitrophenyl)morpholine can be characterized by:

  1. The ability to dissolve well in polar solvents.
  2. Limited solubility in non-polar solvents.
  3. Moderate behavior in aqueous solutions.

Understanding the solubility of this compound is essential for its effective utilization in various chemical applications. As always, empirical testing is advised to quantify solubility in specific solvent systems.

Interesting facts

Interesting Facts About 4-(4-Nitrophenyl)morpholine

4-(4-Nitrophenyl)morpholine is a fascinating organic compound that plays a significant role in various fields of research and application. Here are some intriguing aspects worth noting:

  • Versatile Chemical Structure: The compound features both a nitrophenyl group and a morpholine ring, giving it a unique blend of reactivity and stability. This combination is often exploited in synthetic organic chemistry.
  • Importance in Medicinal Chemistry: Compounds like 4-(4-nitrophenyl)morpholine are often studied for their potential pharmacological properties. Researchers are continually exploring its effects and mechanisms of action, making it a subject of interest in drug development.
  • Applications: This compound can function as a building block for various organic synthesis pathways, serving as an important intermediate in the creation of more complex molecules, including pharmaceuticals and agrochemicals.
  • Noteworthy Evidence: Studies have indicated that nitro-substituted compounds can exhibit significant biological activity, including antimicrobial and anticancer properties. This makes 4-(4-nitrophenyl)morpholine a candidate for further investigation in these areas.
  • Research Contributions: The presence of the nitro group can also influence the compound’s electronic properties, making it a valuable target for experimental research in understanding reaction mechanisms and kinetic profiles.

In summary, 4-(4-nitrophenyl)morpholine is more than just a chemical compound; it is a notable participant in the broader narrative of chemical research. As scientists and students uncover its various facets, they contribute to the ever-expanding knowledge in fields such as pharmacology, organic synthesis, and materials science.

Synonyms
4-(4-Nitrophenyl)morpholine
10389-51-2
Morpholine, 4-(4-nitrophenyl)-
p-Morpholinonitrobenzene
4-(p-Nitrophenyl)morpholine
4-Morpholinyl nitrobenzene
N-(p-Nitrophenyl)-morpholine
MORPHOLINE, 4-(p-NITROPHENYL)-
EINECS 233-851-3
NSC 27271
BRN 0210854
DTXSID5065061
DTXCID8032833
233-851-3
4-Morpholinonitrobenzene
N-(4-Nitrophenyl)morpholine
4-(4-Nitrophenyl) Morpholine
4-Nitrophenylmorpholine
MFCD00023317
QQ5L4U8QQS
MLS002639157
NSC-27271
Maybridge1_001242
UNII-QQ5L4U8QQS
N-(p-Nitrophenyl)morpholine
SCHEMBL85548
4-(p-Nitrophenyl)-morpholin
4-(4-nitrophenyl)-morpholine
SCHEMBL3282015
4-(4-Nitro-phenyl)-morpholine
CHEMBL1871103
SCHEMBL12247909
SCHEMBL27828925
HMS545A10
IAJDSUYFELYZCS-UHFFFAOYSA-
4-(4-nitrophenyl) (morpholine)
HMS3089J16
ALBB-023290
CS-B0266
NSC27271
BTB 05771
CCG-51799
SBB006371
STK123297
AKOS000446114
AC-7242
MS-2079
SMR001488765
ST057427
SY005309
DB-001572
N1124
NS00023265
SR-01000408777
SR-01000408777-1
SR-01000408777-2
InChI=1/C10H12N2O3/c13-12(14)10-3-1-9(2-4-10)11-5-7-15-8-6-11/h1-4H,5-8H2