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Piribedil

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Identification
Molecular formula
C22H30N2O3
CAS number
3605-01-6
IUPAC name
4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one
State
State

At room temperature, piribedil is a solid crystalline compound.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.10
Boiling point (Celsius)
571.20
Boiling point (Kelvin)
844.20
General information
Molecular weight
373.48g/mol
Molar mass
373.4840g/mol
Density
1.1080g/cm3
Appearence

Piribedil appears as a white to off-white crystalline powder. It is relatively stable under normal conditions but should be stored away from light and moisture to prevent degradation. As a powder, it has a finely granulated texture.

Comment on solubility

Solubility of 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

The solubility of 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one can be influenced by various factors, making it a compound of particular interest:

  • Polarity: The presence of multiple methoxy groups in the structure enhances its polarity, which often translates to increased solubility in polar solvents such as water and ethanol.
  • Hydrogen Bonding: The piperazine moiety can participate in hydrogen bonding, potentially increasing solubility in polar solvents.
  • Hydrophobic Character: The o-tolyl and trimethoxyphenyl groups add hydrophobic character, which may reduce solubility in water but improve solubility in organic solvents like dimethyl sulfoxide (DMSO).
  • Temperature Effects: Typically, solubility can increase with temperature; thus, the compound could become more soluble in warmer conditions.

The solubility profile of this compound makes it particularly versatile for formulation in various drug delivery systems. To summarize, it can display:

  • Higher solubility in polar solvents due to its functional groups.
  • Reduced solubility in non-polar conditions due to its larger hydrophobic portions.

Understanding these subtleties in solubility can significantly enhance the compound's practical applications in pharmaceuticals and material sciences.

Interesting facts

Interesting Facts about 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one

This compound, known for its complex structure, has captured the attention of the scientific community due to its potential applications and unique properties. Here are some intriguing points to consider:

  • Pharmacological Potential: The presence of the piperazine moiety in this compound suggests that it may exhibit therapeutic properties, particularly as a *psychotropic agent*. Compounds with similar structures have been studied for their effects on neurotransmitter systems.
  • Structural Diversity: The incorporation of the o-tolyl group and the trimethoxyphenyl group contributes to its unique *chemical behavior*. This diversity can lead to varied interactions with biological targets, enhancing its applicability in drug development.
  • Research Significance: This compound may serve as a valuable tool in the study of *central nervous system disorders*. Its intricate structure allows researchers to explore how modifying certain functional groups can influence biological activity.
  • Synthetic Interest: The synthesis of this compound is an ongoing topic of research, as it requires advanced *organic synthesis techniques*. This process often serves as a practical exercise for chemistry students looking to enhance their skills in complex molecule creation.
  • Potential Side Effects: As with any compound that affects the nervous system, it's crucial to evaluate both the *therapeutic effects* and potential side effects. Understanding how these compounds interact at the molecular level can guide safer usage in future applications.

In summary, 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one stands at the intersection of *synthetic chemistry* and *pharmacology*, offering exciting opportunities for those eager to explore the complexities of chemical compounds. As research continues, it may unveil new pathways towards innovative therapeutic solutions.