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TFMPP dihydrochloride

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Identification
Molecular formula
C20H26Cl2N2O4
CAS number
61969-55-9
IUPAC name
4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one;dihydrochloride
State
State

At room temperature, the compound is usually in a solid state.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
265.00
Boiling point (Kelvin)
538.15
General information
Molecular weight
413.39g/mol
Molar mass
413.3900g/mol
Density
1.2000g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride

The solubility of 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride can be quite complex due to its unique chemical structure. Here are some key points regarding its solubility:

  • Solvent Dependency: This compound is likely to show different solubility behavior in various solvents, often being more soluble in polar solvents such as water or ethanol due to the presence of its dihydrochloride form.
  • Ionization: The dihydrochloride salt enhances solubility by providing additional ionic interactions, thus making it more soluble in aqueous solutions.
  • Temperature Effects: As with many compounds, solubility might increase with temperature, allowing for better dissolution in solvent.
  • pH Sensitivity: Being a piperazine derivative, its solubility may also be affected by the pH of the solution. Adjusting pH can lead to variations in solubility.

For practical applications, it is important to note that the solubility can influence the bioavailability and pharmacokinetics of the compound in pharmaceutical formulations. Therefore, understanding its solubility profile in relevant solvents is essential.

Interesting facts

Interesting Facts about 4-[4-(o-tolyl)piperazin-1-yl]-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride

This compound belongs to a class of chemical entities known as piperazines, which are well-known for their diverse biological activities. Here are some intriguing aspects of this particular dihydrochloride salt:

  • Pharmacological Potential: Many piperazine derivatives have been explored as potential drugs. This compound's unique structure hints at possible applications in the treatment of various neurological disorders.
  • Chemical Versatility: The presence of trimethoxy and o-tolyl groups suggests interesting interactions with biological targets, which can lead to enhanced activity and selectivity in medicinal chemistry.
  • Research Interest: Scientists are particularly interested in compounds like this one for their potential in developing novel anxiolytics or antidepressants, providing opportunities for research and discovery.
  • Structure-Activity Relationship (SAR): Understanding how small changes to the chemical structure can improve efficacy or reduce side effects is a key focus in medicinal chemistry, and this compound serves as an excellent example.

As the world continues to investigate novel compounds for therapeutic use, such structures will undoubtedly play a crucial role in paving the way for future advancements in pharmacology. The blend of functional groups in this compound is a classic reminder of the complex relationship between chemical structure and biological activity, embodying the very essence of medicinal chemistry.

In the words of famous chemist Robert H. Grubbs, "A chemist must be able to make money by the gram, yet a scientist is only as good as his or her ideas." Hence, compounds like this highlight the synergy between creativity and practicality in the realm of science.

Synonyms
17755-90-7
BUTYROPHENONE, 4-(4-(o-TOLYL)PIPERAZINYL)-3',4',5'-TRIMETHOXY-, DIHYDROCHLORIDE
4-(4-(o-Tolyl)piperazinyl)-3',4',5'-trimethoxybutyrophenone dihydrochloride
DTXSID90170342
1-(o-Tolyl)-4-(3-(3,4,5-trimethoxybenzoyl)propyl)piperazine dihydrochloride
Piperazine, 1-(o-tolyl)-4-(3-(3,4,5-trimethoxybenzoyl)propyl)-, dihydrochloride
DTXCID4092833