4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile

Identification

Molecular formula

C₁₈H₁₆N₂

CAS number

129039-00-5

IUPAC name

4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile

State

At room temperature, 4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile is typically found in a solid state.

Melting point (Celsius)

83.00

Melting point (Kelvin)

356.15

Boiling point (Celsius)

451.30

Boiling point (Kelvin)

724.45

General information

Molecular weight

274.34g/mol

Molar mass

274.3420g/mol

Density

1.1490g/cm³

Appearence

4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile appears as a solid compound that is typically white to off-white in color. It is generally crystalline in nature though it may sometimes form as a powder depending on the method of synthesis and purification.

Comment on solubility

Solubility of 4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile

The solubility of 4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile (C₁₈H₁₆N₂) can be influenced by various factors, making it an interesting compound to study. In general, its solubility characteristics can be summarized as follows:

Solvent Dependence: This compound tends to be more soluble in organic solvents like dichloromethane or ethanol compared to water, due to its hydrophobic aromatic structure.
Temperature Effects: Increasing temperature often enhances the solubility of many organic compounds, including this one, as it promotes molecular movement and interaction.
pH Variability: Solubility can be further influenced by the pH of the solution; alterations in pH can affect the ionization states of nitrogen atoms within the structure.

In summary, while the compound shows limited solubility in polar solvents, its affinity for non-polar solvents makes it valuable for various applications in the pharmaceutical and chemical industries. Understanding its solubility profile is crucial for predicting its behavior in different environments and for optimizing its use in formulations.

Interesting facts

Exploring 4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile

4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile is a fascinating compound that belongs to the class of chemical compounds known as pyridine derivatives. This compound, with its unique structure, showcases the intricate relationships between aromaticity and heterocyclic systems. Here are some intriguing facts about this chemical:

Structure Complexity: The compound features a pyridine ring fused with a benzene ring, creating a rich tapestry of electronic interactions that are essential in medicinal chemistry.
Biological Activity: Pyridine derivatives often exhibit significant biological activities, including anticancer, antiviral, and anti-inflammatory properties, making them valuable in drug design and development.
Synthetic Utility: The synthesis of pyridinyl compounds often employs various methods, including multi-step synthesis, which can lead to diverse substituents and functionalization patterns.
Research Interest: Scientists are particularly interested in compounds like this one for their potential to inhibit specific biological pathways, particularly in the fields of neuroscience and cancer research.
Pharmacophore Modeling: Due to its unique structure, this compound serves as a fantastic subject for pharmacophore modeling studies which help in understanding how molecular modifications can impact bioactivity.

In summary, 4-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)benzonitrile serves as a prime example of how complex chemistry can lead to significant advancements in various fields, including pharmaceutical research and development. The ongoing studies surrounding such compounds are essential for unlocking new therapeutic avenues.

Synonyms

BRN 1318739

BENZONITRILE, 4-(4-PHENYL-1,2,5,6-TETRAHYDRO-1-PYRIDYL)-

4-(4-Phenyl-1-(1,2,5,6-tetrahydropyridyl))benzonitrile

10338-61-1

DTXSID40145803

5-20-07-00125 (Beilstein Handbook Reference)

DTXCID4068294