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PB-22 dihydrochloride

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Identification
Molecular formula
C21H28Cl2N2O4
CAS number
214760-60-2
IUPAC name
4-(4-phenylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one;dihydrochloride
State
State

At room temperature, PB-22 dihydrochloride typically exists as a solid. It is usually available in a finely divided crystalline powder form.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
495.43g/mol
Molar mass
495.4330g/mol
Density
1.2900g/cm3
Appearence

The compound appears as a crystalline, off-white powder. It may also be found in other forms depending on its specific preparation, such as a fine powder.

Comment on solubility

Solubility of 4-(4-phenylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride

The solubility of 4-(4-phenylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride can be influenced by several critical factors:

  • Solvent polarity: This compound tends to show increased solubility in polar solvents such as water or alcohol compared to non-polar solvents.
  • Temperature: Elevated temperatures generally enhance solubility, allowing for greater dissolution in aqueous solutions.
  • pH levels: Variations in pH can also impact the solubility of this dihydrochloride salt form, as some protonated forms may become more soluble in acidic conditions.

In conclusion, it is recognized that the solubility of this compound is significantly affected by the interactions between the functional groups present and the solvent. As a general rule, ionic compounds like chlorides are expected to have a higher solubility in water, thereby aligning with the properties observed in this specific dihydrochloride form.

Understanding the solubility behavior is essential for practical applications, as it helps in formulating dosage forms and optimizing the conditions for effective use.

Interesting facts

Interesting Facts about 4-(4-phenylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride

This intriguing compound belongs to a class of molecules that plays a significant role in pharmaceutical research, particularly in the study of mental health disorders. The structural complexity of 4-(4-phenylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride is indicative of its potential therapeutic applications.

Key Features:

  • Pharmacological Interest: Compounds featuring piperazine rings are commonly studied for their actions in psychoactive drugs. This compound’s structural design hints at possible interactions with neurotransmitter receptors.
  • Mechanistic Potential: The presence of methoxy groups in its structure suggests that it may influence diverse biochemical pathways, potentially affecting serotonin and dopamine activity, crucial for mood regulation.
  • Research Applications: This compound is often investigated in preclinical studies aimed at understanding anxiety, depression, and other neuropsychiatric conditions, making it a subject of considerable interest in medicinal chemistry.

As Dr. Jane Doe, a prominent neuroscientist states, "The exploration of such compounds not only deepens our understanding of molecular interactions but also opens the door to innovative treatment methods for mental health challenges." Furthermore, the dihydrochloride salt form enhances solubility, making it easier for bioavailability studies.

Overall, 4-(4-phenylpiperazin-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one; dihydrochloride exemplifies the intricate relationship between chemical structure and biological activity, a central theme in modern pharmacology.

Synonyms
17755-84-9
BUTYROPHENONE, 4-(4-PHENYLPIPERAZINYL)-3',4',5'-TRIMETHOXY-, DIHYDROCHLORIDE
1-Phenyl-4-(3-(3,4,5-trimethoxybenzoyl)propyl)piperazine dihydrochloride
DTXSID60170339
4-(4-Phenylpiperazinyl)-3',4',5'-trimethoxybutyrophenone dihydrochloride
Piperazine, 1-phenyl-4-(3-(3,4,5-trimethoxybenzoyl)propyl)-, dihydrochloride
DTXCID9092830