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Tandospirone

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Identification
Molecular formula
C23H30Cl2N4O4
CAS number
112457-95-1
IUPAC name
4-(4-pyridin-1-ium-2-ylpiperazin-1-ium-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one;dichloride
State
State

At room temperature, tandospirone typically exists as a solid in the form of its dichloride salt. This form enhances its stability and water solubility, making it more suitable for pharmaceutical applications.

Melting point (Celsius)
243.50
Melting point (Kelvin)
516.60
Boiling point (Celsius)
561.15
Boiling point (Kelvin)
834.30
General information
Molecular weight
465.42g/mol
Molar mass
465.4000g/mol
Density
1.2378g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. It is often provided in its dichloride salt form for stability and solubility, which may slightly affect the color or texture.

Comment on solubility

Solubility of 4-(4-pyridin-1-ium-2-ylpiperazin-1-ium-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one;dichloride

The solubility of this complex compound can vary significantly depending on several factors, which makes its profile particularly intriguing. Here are some key considerations:

  • Nature of the Compound: As a salt (dichloride), it is often more soluble in polar solvents, particularly water.
  • Functional Groups: The presence of multiple methoxy groups within the structure can enhance solubility in organic solvents due to their electron-donating properties.
  • pH Dependence: The solubility may also be influenced by the pH of the solution, as both the pyridinium and piperazinic portions may contribute to charge interactions.

In terms of general behavior:

  • Salt forms tend to exhibit higher solubility compared to their neutral counterparts.
  • Polarity factors, especially in relation to the solvent, play a critical role in determining the overall solubility.

As an overview, while specific solubility data for this compound may not be universally detailed in literature, one can expect:

  • Increased solubility in water due to its ionic nature.
  • Considerable solubility in a variety of organic solvents due to its aromatic and aliphatic structures.

These factors highlight the importance of considering both the molecular structure and the environment when assessing the solubility of chemical compounds like 4-(4-pyridin-1-ium-2-ylpiperazin-1-ium-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one;dichloride.

Interesting facts

Interesting Facts about 4-(4-pyridin-1-ium-2-ylpiperazin-1-ium-1-yl)-1-(3,4,5-trimethoxyphenyl)butan-1-one;dichloride

This fascinating compound, often referred to by its shorthand or structural notation, has captured the attention of scientists due to its unique architecture and functional properties. Here are some noteworthy aspects:

  • Diverse Applications: Compounds of this nature typically engage in a variety of biological activities, showcasing potential as pharmaceuticals and agrochemicals. Researchers believe it could be pivotal in treating neurological disorders.
  • Molecular Complexity: The intricate structure of this compound speaks to the beauty of organic synthesis. With multiple functional groups, it demonstrates the interplay between aromatic systems and heterocycles, emphasizing the synergy of chemistry.
  • Research Interest: Studies indicate that compounds with pyridin-ium and piperazin-ium moieties may exhibit interesting anti-cancer and anti-inflammatory properties, making it a hot topic for further investigation in medicinal chemistry.
  • Structure-Activity Relationship (SAR): Understanding how variations in structure affect biological activity is crucial. This compound serves as a fine example for SAR studies, shedding light on modifications that enhance efficacy.
  • Synthesis Challenges: The synthesis of such complex molecules often poses significant challenges. Chemists must optimize reaction conditions to achieve high yields while ensuring the stability of sensitive functional groups.

Overall, the study of this compound not only enriches our understanding of organic chemistry but also opens doors to potential therapeutic advancements. Just as John Dalton once remarked about the wonders of atoms, "It is enough to be a student of nature to reflect how wonderful it is!"

In conclusion, exploring compounds like this one invites us to delve deeper into the intricate world of molecular interactions and their implications in science and medicine.

Synonyms
Butyrophenone, 4-(4-(2-pyridyl)piperazinyl)-3',4',5'-trimethoxy-, dihydrochloride
16785-30-1
1-(2-Pyridyl)-4-(3-(3,4,5-trimethoxybenzoyl)propyl)piperazine dihydrochloirde
4-(4-(2-Pyridyl)piperazinyl)-3',4',5'-trimethoxybutyrophenone dihydrochloride
Piperazine, 1-(2-pyridyl)-4-(3-(3,4,5-trimethoxybenzoyl)propyl)-, dihydrochloride