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5-Methoxy-N,N-dimethyltryptamine hydrochloride

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Identification
Molecular formula
C13H19ClN2O
CAS number
1019-45-0
IUPAC name
4-(5-methoxy-1H-indol-3-yl)butylammonium;chloride
State
State

At room temperature, this compound is typically a solid. Due to its crystalline structure, it remains stable under normal conditions and should be handled with care to avoid dust formation.

Melting point (Celsius)
186.00
Melting point (Kelvin)
459.15
Boiling point (Celsius)
410.15
Boiling point (Kelvin)
683.30
General information
Molecular weight
267.77g/mol
Molar mass
267.7700g/mol
Density
1.2820g/cm3
Appearence

4-(5-methoxy-1H-indol-3-yl)butylammonium chloride appears as a white to off-white crystalline powder. It is usually fine and uniform, with moderate opacity.

Comment on solubility

Solubility of 4-(5-methoxy-1H-indol-3-yl)butylammonium chloride

The solubility of 4-(5-methoxy-1H-indol-3-yl)butylammonium chloride can be quite intriguing due to its specific structural components and ionic nature. Here are some key points to consider:

  • Ionic Nature: As a quaternary ammonium salt, this compound is likely to exhibit high solubility in polar solvents such as water due to the ion-dipole interactions between the positively charged ammonium group and water molecules.
  • Hydrophilicity: The presence of the butylammonium group contributes to the compound's overall hydrophilic character, enhancing its solubility in aqueous solutions.
  • Effect of the Indole Moiety: The 5-methoxy-1H-indole moiety may introduce some steric hindrance, potentially affecting the solubility slightly, but generally, indole derivatives tend to be soluble in organic solvents.

Researchers often observe that:

  1. In aqueous media, quaternary ammonium salts show preferential solubility.
  2. In organic solvents, solubility may vary based on the solvent's polarity.

Overall, it can be concluded that this compound's solubility profile is predominantly influenced by its ionic nature and the presence of hydrophilic groups. As it is stated, "Solubility is key to bioavailability," making it essential in pharmacological contexts.

Interesting facts

Interesting Facts About 4-(5-Methoxy-1H-Indol-3-Yl)Butylammonium Chloride

4-(5-Methoxy-1H-indol-3-yl)butylammonium chloride is a fascinating compound that belongs to the class of indole derivatives, which are well-known for their diverse biological activities. Here are several interesting aspects of this compound:

  • Indole Backbone: The presence of an indole ring, which is a bicyclic structure, in this compound contributes significantly to its biological properties. Indole derivatives are often found in natural compounds and play critical roles in various physiological processes.
  • Biological Significance: Compounds containing indole are known for their ability to modulate various receptors and enzymes in the body, making them important in pharmaceutical research. The 5-methoxy group may affect the pharmacological activity related to neurotransmitter systems.
  • Potential Applications: Due to its structural features, this compound shows potential for applications in drug development. Researchers are interested in its effects on neurotransmission and its capability to act as an ion-channel modulator.
  • Novelty: The butylammonium group enhances the compound's interaction potential with biological membranes, influencing its absorption and distribution within biological systems.
  • Research Interest: As a part of ongoing research, the exploration of 4-(5-methoxy-1H-indol-3-yl)butylammonium chloride may lead to the discovery of new therapeutic agents or insights into biochemical pathways.

In summary, 4-(5-methoxy-1H-indol-3-yl)butylammonium chloride presents not only structural complexity but also a potential bridge between synthetic chemistry and biochemical efficacy. Its investigation could unravel new avenues in medicinal chemistry, reinforcing the connections between compound structure and biological function.

Synonyms
1H-INDOLE, 3-(4-AMINOBUTYL)-5-METHOXY-, MONOHYDROCHLORIDE
16536-90-6
3-(4-Aminobutyl)-5-methoxyindole monohydrochloride