Skip to main content

Sulfamethoxazole

ADVERTISEMENT
Identification
Molecular formula
C10H11N3O3S
CAS number
723-46-6
IUPAC name
4-[(5-methylisoxazol-3-yl)methylsulfonyl]aniline;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
State
State

At room temperature, sulfamethoxazole is a solid. It is typically provided in powder form for pharmaceutical preparations.

Melting point (Celsius)
169.00
Melting point (Kelvin)
442.15
Boiling point (Celsius)
605.00
Boiling point (Kelvin)
878.15
General information
Molecular weight
253.28g/mol
Molar mass
253.2830g/mol
Density
1.4900g/cm3
Appearence

Sulfamethoxazole appears as a white to off-white crystalline powder. It is practically odorless and has a bitter taste. The compound is sparingly soluble in water but dissolves in acetone and dilute acids.

Comment on solubility

Solubility of 4-[(5-methylisoxazol-3-yl)methylsulfonyl]aniline; 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

The solubility of the compound 4-[(5-methylisoxazol-3-yl)methylsulfonyl]aniline; 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine is influenced by its complex molecular structure and the presence of various functional groups. Understanding its solubility can provide insights into its potential applications and behavior in different environments.

Factors Affecting Solubility:

  • Polarity: The presence of polar groups, such as the sulfonyl (-SO2-) and amine groups (-NH2-), may enhance solubility in polar solvents like water.
  • Hydrogen Bonding: Compounds capable of forming hydrogen bonds generally exhibit improved solubility in water.
  • Molecular Weight: Higher molecular weight can decrease solubility due to increased van der Waals forces.

It is also noteworthy that solubility is not an absolute measure, and can be affected by the solvent used:

  • Water: Given its polar groups, this compound might show a moderate degree of solubility.
  • Organic Solvents: It may demonstrate higher solubility in organic solvents due to its hydrophobic aromatic components.

Therefore, while the exact solubility will depend on specific conditions, understanding these general principles can help predict how this compound will behave in various solvents. As one may say, “Solubility is the key to the behavior of a compound in a medium.”

Interesting facts

Interesting Facts about 4-[(5-methylisoxazol-3-yl)methylsulfonyl]aniline; 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine

This compound, with its complex structure, is a fascinating example of modern medicinal chemistry. Here are some engaging facts:

  • Pharmacological Potential: This compound is a part of ongoing research for its potential use in treating various diseases, notably certain types of cancer and inflammatory conditions. The presence of both sulfonyl and isoxazole groups contributes to the increased biological activity.
  • Structure-Activity Relationship: Chemists pay close attention to the relationship between a compound's structure and its biological activity. The specific arrangement of methyl groups and the pyrimidine ring plays a critical role in enhancing the potency of this compound.
  • Versatile Synthesis: The synthetic routes developed for creating this compound often involve multi-step reaction pathways, showcasing the creative ingenuity of chemists in constructing complex molecules from simpler ones.
  • Interdisciplinary Nature: The study of this compound lies at the intersection of chemistry, biology, and medicine. Its development involves not only organic synthesis but also biological testing and medical application, emphasizing the collaborative effort across different scientific fields.
  • Emerging Research: As scientists delve deeper into the effects and mechanisms of this compound, new applications and insights may arise, making it a subject of interest in pharmaceutical development.

In conclusion, the intricate design and potential therapeutic benefits of 4-[(5-methylisoxazol-3-yl)methylsulfonyl]aniline; 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine exemplify how chemical compounds can significantly impact modern medicine and highlight the continuous evolution of chemical research in improving human health.

Synonyms
PD202751
NS00078748