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4-[(5-nitro-1H-indol-3-yl)methyl]morpholine

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Identification
Molecular formula
C13H15N3O3
CAS number
100331-89-3
IUPAC name
4-[(5-nitro-1H-indol-3-yl)methyl]morpholine
State
State

This compound is a solid at room temperature, exhibiting a crystalline form. It maintains its structure without melting under normal ambient conditions.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
536.00
Boiling point (Kelvin)
809.15
General information
Molecular weight
259.28g/mol
Molar mass
259.2650g/mol
Density
1.4400g/cm3
Appearence

The compound typically appears as a crystalline solid with a light yellow or off-white color. It can form well-defined crystalline structures and may have a dull shine or matte finish.

Comment on solubility

Solubility of 4-[(5-nitro-1H-indol-3-yl)methyl]morpholine

The solubility of 4-[(5-nitro-1H-indol-3-yl)methyl]morpholine is an intriguing topic due to its structural complexity and functional groups that can influence its behavior in various solvents. Generally, the solubility of a compound in a particular solvent can be influenced by the following factors:

  • Polarity: This compound contains both polar (morpholine) and non-polar (indole) components, suggesting that it may have moderate solubility in polar solvents like water or methanol.
  • Functional Groups: The presence of the nitro group may enhance solubility in polar solvents due to its electron-withdrawing effects, whereas its hydrophobic indole moiety might promote solubility in organic solvents.
  • Hydrogen Bonding: Morpholine has the ability to participate in hydrogen bonding, which could increase solubility in polar protic solvents.

In practical terms, it is often noted that:

  • Compounds with strong hydrogen bonds tend to have higher solubility in polar solvents.
  • Conversely, compounds with larger hydrophobic tails often show enhanced solubility in organic solvents.

Therefore, while a precise solubility value for 4-[(5-nitro-1H-indol-3-yl)methyl]morpholine would require experimental determination, one might expect it to exhibit:

  • Moderate solubility in polar solvents due to its morpholine and nitro functionalities.
  • Variable solubility in non-polar solvents influenced by its indole structure.

In conclusion, understanding the solubility of this compound can provide insights into its potential applications in various chemical and biological contexts.

Interesting facts

Interesting Facts about 4-[(5-nitro-1H-indol-3-yl)methyl]morpholine

4-[(5-nitro-1H-indol-3-yl)methyl]morpholine is a fascinating compound with a variety of intriguing attributes that make it worth studying in the realm of chemistry.

Key Characteristics

  • Structural Significance: This compound features both an indole and morpholine structure, which can allow for interesting interactions in biological systems.
  • Biological Potential: The nitro group attached to the indole ring can modify the compound's activity, making it a candidate for pharmacological applications.
  • Versatile Synthesis: The synthesis of this compound can provide insights into multistep organic reactions, showcasing the intricacies of building complex molecules.

Applications

  • Pharmaceutical Research: Due to its structural components, this compound is often explored for its potential therapeutic effects, particularly as it relates to cancer treatment and other health disorders.
  • Material Science: Insights gained from studying this compound can potentially lead to the development of new materials with tailored properties.
  • Analytical Chemistry: The unique structure of this compound makes it a valuable candidate for various analytical techniques, helping chemists understand reaction mechanisms.

As chemists continue to explore the properties and potential applications of 4-[(5-nitro-1H-indol-3-yl)methyl]morpholine, it serves as a vivid reminder of the complex and interconnected web of chemical compounds that shape our understanding of both science and industry.

In the words of renowned chemist Linus Pauling, “The best way to have a good idea is to have lots of ideas.” The study of compounds like this one fuels creativity and innovation in the field of chemistry.

Synonyms
3414-70-8
4-((5-Nitro-1H-indol-3-yl)methyl)morpholine
INDOLE, 3-(MORPHOLINOMETHYL)-5-NITRO-
4-[(5-nitro-1H-indol-3-yl)methyl]morpholine
3-[(morpholin-4-yl)methyl]-5-nitro-1H-indole
BRN 1592116
3-(Morpholinomethyl)-5-nitroindole
5-Nitro-3-(morpholinomethyl)indole
SCHEMBL19252919
DTXSID50187734