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Rufinamide

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Identification
Molecular formula
C10H8N2O3
CAS number
64603-89-0
IUPAC name
4-(5-nitro-2-furyl)but-3-en-2-one
State
State

At room temperature, Rufinamide is in a solid state in the form of a crystalline powder.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
380.00
Boiling point (Kelvin)
653.15
General information
Molecular weight
238.20g/mol
Molar mass
238.2040g/mol
Density
1.3730g/cm3
Appearence

Rufinamide typically appears as a white to off-white crystalline powder. It is a stable compound that is relatively insoluble in water at room temperature.

Comment on solubility

Solubility of 4-(5-nitro-2-furyl)but-3-en-2-one

The solubility of 4-(5-nitro-2-furyl)but-3-en-2-one can greatly affect its applications in various chemical processes. To understand its solubility characteristics, consider the following factors:

  • Polarity: The presence of a nitro group (-NO2) in the structure introduces considerable polarity, which may enhance solubility in polar solvents.
  • Hydrogen Bonding: The compound may engage in hydrogen bonding due to the functional groups involved, impacting its interaction with solvents.
  • Solvent Choice: This compound is likely to be more soluble in organic solvents such as ethanol or acetone rather than in water due to its non-polar characteristics, despite its polar functional group.

In conclusion, while 4-(5-nitro-2-furyl)but-3-en-2-one may demonstrate variable solubility primarily influenced by its molecular structure and the solvent nature, it is advisable to perform empirical solubility tests to confirm the theoretical predictions. As stated in the literature, "the key to successful solubility lies in understanding the nature of both the solute and the solvent." Thus, testing its solubility in different media would provide invaluable insights.

Interesting facts

Interesting Facts about 4-(5-nitro-2-furyl)but-3-en-2-one

4-(5-nitro-2-furyl)but-3-en-2-one is a fascinating compound that showcases the intricate relationship between organic chemistry and biological activity. Here are some intriguing aspects of this compound:

  • Structural Diversity: The compound features a unique combination of functional groups, including a furan ring, which contributes to its reactivity and potential applications in synthetic organic chemistry.
  • Biological Potential: Compounds like 4-(5-nitro-2-furyl)but-3-en-2-one have been studied for their anti-cancer properties. The nitro group can enhance electron-withdrawing effects, possibly leading to the activation of specific biological pathways.
  • Synthetic Applications: This compound can serve as an important intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its distinct structure opens avenues for further derivatization to create molecules with desirable properties.
  • Reactivity and Mechanism: The presence of the α,β-unsaturated carbonyl moiety makes this compound a versatile substrate for Michael additions, allowing for diverse reaction pathways in synthetic chemistry.
  • Research Usage: Scholars often use this compound in experimental setups to investigate reaction mechanisms or the reactivity of furan derivatives, highlighting its importance in educational settings.

The exploration of 4-(5-nitro-2-furyl)but-3-en-2-one not only reflects the beauty of organic synthesis but also illustrates the significant roles such compounds can play in advancing medicinal chemistry and agricultural science. As research continues, new applications for this compound may unveil exciting horizons in both molecular science and practical use!

Synonyms
5-nitrofurfurylideneacetone
DTXSID601292622
AKOS017268853
4-(5-Nitro-2-furyl)-3-buten-2-one
4-(5-Nitro-2-furanyl)-3-buten-2-one