Celecoxib
- Molecular formula
- C17H14F3N3O2S
- CAS Number
- 169590-42-5
- IUPAC Name
- 4-[5-(p-tolyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
- Molecular Weight
- 381.37g/mol
- Melting Point
- (Celsius)
- Boiling Point
- (Celsius)
- Density
- 1.4000g/cm3
- Synonyms
- celecoxib
Identification
Interesting Facts about 4-[5-(p-tolyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
This fascinating compound, known for its intricate structure, belongs to the class of sulfonamides, which are crucial in medicinal chemistry. Here are some notable points about its significance:
- Pharmaceutical Potential: Sulfonamides, including this compound, have shown promise as antibacterial agents. Their ability to inhibit bacterial growth by interfering with folic acid synthesis makes them invaluable in drug development.
- Trifluoromethyl Group: The presence of the trifluoromethyl group enhances the lipophilicity of the compound, potentially affecting its bioavailability and pharmacokinetics.
- Pyrazole Motif: The pyrazole ring is noteworthy for its biological activity, and compounds featuring this functional group are often involved in anti-inflammatory and antitumor activities.
- p-Tolyl Substitution: The p-tolyl group contributes to the chemical's reactivity and stability, showcasing the importance of substituents in modulating the properties of complex organic molecules.
This compound exemplifies how modifying a molecular framework can lead to diverse biological properties. The ongoing research into its applications in various fields, particularly in developing new antibiotics and therapeutic agents, makes it a compound of great interest. As a chemistry student or scientist, one might say, "Understanding the interaction of such compounds with biological targets is key to innovating new treatments."
Overall, 4-[5-(p-tolyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide represents a harmonious blend of chemistry and biology, paving the way for advancements in therapeutic interventions.