Interesting facts
Interesting Facts about 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol
This complex compound, characterized by its unique structure, holds significant promise in the field of medicinal chemistry. Here are some intriguing facts about its properties and applications:
- Pharmacological Potential: The intricate design of this compound suggests that it may interact with biological systems in novel ways. Compounds with a similar structure have been studied for their potential as anticancer agents, specifically by targeting certain cellular pathways.
- Multi-Target Activity: The presence of multiple benzimidazole moieties in the structure can enhance the compound's ability to bind to different targets, which is crucial for developing drugs that can tackle complex diseases with multifactorial origins.
- Role in Neuroscience: The incorporation of a piperazine ring hints at possible neuroactive properties. Piperazines are often utilized in medicinal chemistry for designing compounds that modulate neurotransmitter systems, which could offer insights into new psychiatric or neurological therapies.
- Structure-Activity Relationship (SAR): Studying compounds like this leads to a better understanding of how subtle changes in chemical structure can influence biological activity, a key concept in drug development.
- Research Opportunities: As this compound is further explored, it may pave the way for new pharmaceutical formulations or therapeutic agents. Its unique structure warrants thorough investigation to uncover potential benefits.
In summary, 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol stands out as a fascinating compound that exemplifies the intersection of chemistry and biology, highlighting the innovative approaches being taken in the development of new therapeutic agents.
Synonyms
Pibenzimol
HOECHST 33258
Bisbenzimidazole
23491-44-3
Hoe-33258
CHEBI:52082
UNII-LHQ7J5KV9B
EINECS 245-689-0
CCRIS 8389
Bisbenzimide (Salt/Mix)
LHQ7J5KV9B
Pibenzimol HCl (Salt/Mix)
4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol
Phenol, 4-(5-(4-methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)-
Phenol, 4-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]-
p-(5-(5-(4-Methyl-1-piperazinyl)-2-benzimidazolyl)-2-benzimidazolyl)phenol
Hoechst Dye 33258
DTXSID3066899
NSC-322921
4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol
bisBenzimide H 33258;H 33258
SL-1063
SL-11063
Bisbenzimidazole trihydrochloride (Salt/Mix)
NSC322921
4-[5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzimidazol-2'-yl]phenol
Phenol, p-(5-(5-(4-methyl-1-piperazinyl)-2-benzimidazolyl)-2-benzimidazolyl)-
4-(5-(4-Methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenol
Bis-Benzimide
2'-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE
2-(2-(4-HYDROXYPHENYL)-6-BENZIMIDAZOLYL)-6-(1-METHYL-4-PIPERAZINYL)BENZIMIDAZOLE
2-(2-(4-HYDROXYPHENYL)-6-BENZIMIDAZOLYL)-6-(1-METHYL-4-PIPERAZYL)BENZIMIDAZOLE
2-[2-(4-Hydroxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazyl)benzimidazole
Hoechst 33258 (trihydrochloride)
NSC 322921
Phenol, p-[5-[5-(4-methyl-1-piperazinyl)-2-benzimidazolyl]-2-benzimidazolyl]-, trihydrochloride
4-(5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzimidazol-2'-yl)phenol
Phenol, p-[5-[5-(4-methyl-1-piperazinyl)-2-benzimidazolyl]-2-benzimidazolyl]-
Phenol, p-(5-(5-(4-methyl-1-piperazinyl)-2-benzimidazolyl)-2-benzimidazolyl)-, trihydrochloride
p-(5-(5-(4-Methylpiperazin-1-yl)benzimidazol-2-yl)benzimidazol-2-yl)phenol
NCIStruc1_000146
NCIStruc2_001668
PHENOL,4-[5-(4-METHYL-1-PIPERAZINYL)[2,5'-BI-1H-BENZIMIDAZOL]-2'-YL]-
SCHEMBL74554
KBioGR_002443
KBioSS_002449
Bisbenzimide (trihydrochloride)
CHEMBL301735
SCHEMBL5332220
DTXCID6036881
SCHEMBL13856958
SCHEMBL18089342
HOE 33258 (trihydrochloride)
KBio2_002443
KBio2_005011
KBio2_007579
KBio3_002921
cMAP_000054
BDBM50498270
CCG-37532
NCGC00014751
NCI322921
AKOS024285175
CS-1301
NCGC00014751-02
NCGC00097852-01
HY-15558
LS-15104
NCI60_002801
PD118617
DB-046162
Hoechst 33258 solution, 1 mg/ml in water
NS00027434
F76803
BRD-K17026858-001-01-2
Q27123162
2'-(4-hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1h-benzimidazole
4-[6-(4-methylpiperazin-1-yl)-1H,3'H-2,5'-bibenzimidazol-2'-yl]phenol
4-(5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazol-2'-yl)phenol
4-(5-(5-(4-Methylpiperazin-1-yl)benzimidazol-2-yl)benzimidazol-2-yl)phenol
4-[5-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol
p-(5-(5-(4-Methyl-1-piperazinyl)-1H-2-benzimidazolyl)-1H-2-benzimidazolyl)phenol
245-689-0
Solubility of 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol (C26H22N6O)
The solubility of the compound 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol is influenced by several factors, including its molecular structure and functional groups. Here are some key points to consider:
Overall, understanding the solubility of this compound is essential for its application in various fields, including pharmaceuticals and materials science. As one study explains, "The solubility profile of a compound can dictate its bioavailability and effectiveness in biological systems."
Further experimental evaluation is necessary to accurately determine its solubility in various solvents and conditions.