Interesting facts
Exploring 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol;trihydrochloride
This fascinating compound, with a complex structure, belongs to the family of benzimidazoles, which are known for their diverse biological activities. Here are some interesting facts about this unique compound:
- Multi-Functional Properties: Benzimidazole derivatives are often recognized for their pharmacological properties, including antibacterial, antiviral, and anticancer activities. This compound, in particular, highlights the importance of molecular structure in drug design.
- Role of Piperazine: The presence of a 4-methylpiperazine moiety enhances the compound's ability to interact with various biological targets. Piperazines are known for their ability to modulate neurotransmitter receptors, which may play a role in pharmacological effects.
- Trihydrochloride Form: The trihydrochloride salt form can enhance solubility in aqueous environments, which is crucial for its bioavailability and subsequent effectiveness in medicinal applications.
- Versatile Applications: Compounds like this one are often utilized in medicinal chemistry and drug discovery, particularly in the search for new therapeutic agents targeting cancer or neurological disorders.
- Structure-Activity Relationship: The complexity of this molecule provides a rich field for studying how various structural modifications can influence biological activity. This can lead to the development of more potent and selective agents.
As a scientist or chemistry student, it is essential to appreciate the intricate design and potential of compounds like 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol;trihydrochloride. The world of chemical compounds is vast and full of potential, showcasing how small changes in structure can lead to significant differences in behavior and application.
Synonyms
Bisbenzimidazole trihydrochloride
33258 Hoechst
Hoechst Dye 33258
H 33258
DTXSID5066900
4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol, trihydrochloride
RefChem:917309
DTXCID1036882
23491-45-4
HOECHST 33258
HOE 33258
Hoechst 33258 Trihydrochloride
bisBenzimide H 33258
Pibenzimol hydrochloride
Bisbenzimide HCl
MFCD00012679
NSC-322921
MHT095273M
Bisbenzimide H 33258 trihydrochloride
Hoechst 33258 (trihydrochloride)
23491-45-4 (HCl)
4-(5-(4-Methylpiperazin-1-yl)-1H,1'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenol trihydrochloride
4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol;trihydrochloride
Bisbenzimide H 33258 Fluorochrome trihydrochloride
CHEMBL34922
4-[6-(4-methyl-1-piperazinyl)[2,6'-bi-1H-benzimidazol]-2'-yl]-phenol, trihydrochloride
Phenol, 4-(6-(4-methyl-1-piperazinyl)(2,6'-bi-1H-benzimidazol)-2'-yl)-, hydrochloride (1:3)
BBIH
MFCD00044760
EINECS 245-690-6
Bis-Benzimide H 33258
UNII-MHT095273M
PIBENZIMOL TRIHYDROCHLORIDE
Hoechst 33258 UltraPure
C25H27Cl3N6O
C25H24N6O 3HCl
HOECHST-33258
orb1303223
SCHEMBL1439775
SCHEMBL18260103
SCHEMBL29443416
SCHEMBL30597851
BXI-72?
OKQAASMPIOSOEX-UHFFFAOYSA-N
Hoechst 33258, UltraPure grade
BISBENZIMIDE TRIHYDROCHLORIDE
BCP19630
EX-A2897
HB0786
HY-15558A
AKOS015903038
AKOS030210959
AKOS030632783
CS-7568
FH36311
4-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol trihydrochloride
p-(5-(4-Methyl-1-piperazinyl)(2,5'-bi-1H-benzimidazol)-2'-yl)phenol trihydrochloride
AS-75157
BISBENZIMIDE TRIHYDROCHLORIDE [MI]
HO-33258
SY057920
DB-046163
B6236
H1343
C74213
491H454
A912877
H-33258
Q27284034
Hoechst 33258 trihydrochloride; H 33258 trihydrochloride
2-(2-(4-HYDROXYPHENYL)-6-BENZIMIDAZOLYL)-6-(1-METHYL-4-PIPERZYL)
Bisbenzimide H 33258 (0.2mL*5) (1mg/mL in Water) [for Cell Staining]
Bisbenzimide H 33258 Fluorochrome, Trihydrochloride - CAS 23491-45-4
2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole Trihydrochloride
2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bibenzimidazole Trihydrochloride
(2'-(4-Hydroxyphenyl)-5-(4-Methyl-1-Piperazinyl)-2,5'-Bi(1H-Benzimidazole) Trihydrochloride
2 inverted exclamation mark -(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5 inverted exclamation mark -bibenzimidazole Trihydrochloride
2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi(1H-benzimidazole) trihydrochloride
2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazole trihydrochloride
4-(5-(4-METHYL-1-PIPERAZINYL) (2,5'-BI-1H-BENZIMIDAZOL)-2'-YL)-PHENOL, TRIHYDROCHLORIDE
4-{6-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1H-1,3-benzodiazol-2-yl}phenol trihydrochloride
Bisbenzimide trihydrochloride;bisBenzimide H 33258 trihydrochloride; H 33258 trihydrochloride; Pibenzimol trihydrochloride
Bisbenzimide;p-(5-(5-(4-Methyl-1-piperazinyl)-1H-2-benzimidazolyl)-1H-2-benzimidazolyl)phenol trihydrochloride
p-(5-(5-(4-methyl-1-piperazinyl)-1h-2-benzimidazolyl)-1h-2-benzimidazolyl)phenol trihydrochloride
Solubility of 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol;trihydrochloride
The solubility of the compound 4-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]phenol;trihydrochloride can be significantly influenced by its structural characteristics. This compound is a salt form, indicated by the presence of trihydrochloride, which often enhances solubility in polar solvents. Here’s what makes this compound particularly noteworthy:
In summary, this compound is likely to exhibit good solubility in aqueous solutions due to its ionic nature and favorable interactions with water. While actual solubility data may vary, the aforementioned factors contribute positively to its solubilization tendencies. Always consider performing empirical solubility tests to obtain accurate and practical results.