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Sulfapyrimidine

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Identification
Molecular formula
C10H11N5O2S
CAS number
80-35-3
IUPAC name
4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide
State
State

At room temperature, sulfapyrimidine is found in a solid state. It is typically supplied as a powder or crystalline substance, making it suitable for use in various chemical and pharmaceutical applications.

Melting point (Celsius)
234.00
Melting point (Kelvin)
507.00
Boiling point (Celsius)
-1.00
Boiling point (Kelvin)
-1.00
General information
Molecular weight
249.29g/mol
Molar mass
249.2770g/mol
Density
1.5000g/cm3
Appearence

Sulfapyrimidine typically appears as a crystalline solid. Its color can range from white to slightly off-white or pale yellow, depending on its purity and the presence of impurities.

Comment on solubility

Solubility of 4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide

The compound 4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide, with the chemical formula C10H11N5O2S, exhibits intriguing solubility characteristics owing to its complex structure.

Key Points on Solubility:

  • Solvent Interaction: This compound is generally soluble in polar solvents such as water and ethanol. The presence of functional groups like -NH2 and -SO2N allow for favorable hydrogen bonding with water molecules.
  • Temperature Dependency: The solubility may increase with temperature, making it crucial to consider the specific conditions under which dissolution is desired.
  • Effect of pH: The presence of amino and sulfonamide groups means that the solubility can be significantly affected by pH changes. A more alkaline environment can enhance solubility due to deprotonation.
  • Crystallization: Under certain conditions, this compound may crystallize, which could lead to reduced solubility at lower temperatures.

In conclusion, the solubility of 4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide in various solvents is a vital consideration for its practical applications. Understanding the factors influencing its solubility is essential for its effective utilization in pharmaceutical and chemical processes.

Interesting facts

Interesting Facts about 4-[(6-Aminopyrimidin-4-yl)amino]benzenesulfonamide

This intriguing compound, known as 4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide, is noteworthy for several reasons:

  • Pharmaceutical Relevance: It belongs to the class of sulfonamide antibiotics, playing a significant role in the treatment of bacterial infections. Its unique structure allows for interaction with bacterial enzyme systems, effectively inhibiting their growth.
  • Pyrimidine Backbone: The presence of the pyrimidine ring provides this compound with notable stability and enhances its biological activity. Pyrimidines are essential in many biological processes, including DNA and RNA synthesis.
  • Multi-functional Grouping: The compound features both an amino group and a sulfonamide group. These functional groups contribute to its solubility and reactivity, making it easier for the compound to interact with various biochemical pathways.

Additionally, scientists often explore the potential of similar compounds in drug discovery, revealing numerous possibilities:

  • Enhanced antibacterial properties
  • Potential antifungal and antiviral applications
  • Development of novel treatment strategies for resistant bacterial strains

Because of these attributes, 4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide is a compound of significant interest in medicinal chemistry research. As renowned chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This compound is a testament to the creativity and innovation that drive the exploration of new therapeutic agents in the fight against diseases.

Synonyms
400611-95-2
4-[(6-AMINO-4-PYRIMIDINYL)AMINO]BENZENESULFONAMIDE
4-((6-Aminopyrimidin-4-yl)amino)benzenesulfonamide
4-[(6-aminopyrimidin-4-yl)amino]benzenesulfonamide
CHEMBL265964
4-((6-Amino-4-Pyrimidinyl)Amino)Benzenesulfonamide
4-((6-aminopyrimidin-4-yl)amino)benzene-1-sulfonamide
4-[(6-aminopyrimidin-4-yl)amino]benzene-1-sulfonamide
1jsv
U55
SCHEMBL1395316
HMS2043P03
BDBM50503351
HSCI1_000197
PNU-112455A?
DB03307
SB60232
PD007101
NS00068276
BRD-K71860425-001-01-1
Q27094236