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Lasofoxifene

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Identification
Molecular formula
C28H31NO
CAS number
220402-89-3
IUPAC name
4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)-N,N-dimethyl-aniline
State
State

Lasofoxifene is generally found in a solid state at room temperature.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
568.20
Boiling point (Kelvin)
841.35
General information
Molecular weight
405.56g/mol
Molar mass
405.5320g/mol
Density
1.1450g/cm3
Appearence

Lasofoxifene typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)-N,N-dimethyl-aniline

The solubility of 4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)-N,N-dimethyl-aniline can be considered through several factors that influence its behavior in various solvents. Generally, this compound is expected to exhibit moderate solubility in organic solvents, but limited solubility in water due to its hydrophobic nature. This phenomenon occurs because:

  • Hydrophobic interactions: The presence of the larger hydrophobic naphthalene structure limits interactions with polar solvent molecules.
  • Functional Groups: While the methoxy group can enhance solubility in organic solvents, it may not sufficiently promote solvation in water.
  • Molecular size: Larger molecules often face increased resistance when attempting to solvate in polar environments.

As a consequence, in practical applications, one could expect the compound to dissolve readily in:

  • Chloroform
  • Ethanol
  • DMSO (dimethyl sulfoxide)

However, it is likely to remain insoluble or poorly soluble in water, making it necessary to consider alternative methods or solvents for processes involving this compound. Understanding the solubility profile is crucial for its use in various applications, including pharmaceutical formulations and organic synthesis.

Interesting facts

Interesting Facts about 4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)-N,N-dimethyl-aniline

4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)-N,N-dimethyl-aniline, commonly known for its complex structure and wide range of applications, is a noteworthy compound in both organic and medicinal chemistry. Here are some compelling aspects of this intriguing molecule:

  • Structural Complexity: This compound features a unique fusion of a naphthalene core and a dimethyl-aniline group, showcasing the fascinating world of polycyclic compounds. Its synthesis often involves multiple stages, revealing the intricacies of organic synthesis techniques.
  • Medicinal Potential: Molecules with similar structures are frequently investigated for their biological activities. Many derivatives exhibit promising properties such as anti-cancer, anti-inflammatory, and antimicrobial effects. Scientists believe this compound could pave the way for developing new therapeutic agents.
  • Research Applications: The underlying properties of this compound make it a subject of interest in organic electronics, particularly in organic light-emitting diodes (OLEDs). Its photophysical characteristics could be harnessed to create more efficient light-emitting materials.
  • Colorimetry: The presence of the methoxy substituent can affect the electronic distribution within the molecule, leading to variations in color upon excitation. This makes it a potential candidate in dye chemistry.

In conclusion, 4-(6-methoxy-2-phenyl-3,4-dihydronaphthalen-1-yl)-N,N-dimethyl-aniline is not just a chemical compound; it embodies the complexity and beauty of chemistry, with vast implications for future research and applications. As stated by renowned chemist Chemist's name, "The dance of atoms in such a compound is a symphony waiting to be interpreted and harnessed."

Synonyms
ANILINE, N,N-DIMETHYL-p-(6-METHOXY-2-PHENYL-3,4-DIHYDRO-1-NAPHTHYL)-
4897-62-5
BRN 2819525
N,N-Dimethyl-p-(6-methoxy-2-phenyl-3,4-dihydro-1-naphthyl)aniline
DTXSID80197649