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Sulfanilic acid

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Identification
Molecular formula
C6H7NO3S
CAS number
121-57-3
IUPAC name
4-acetamidobenzenesulfonic acid
State
State

At room temperature, sulfanilic acid is typically in a solid state. It is known for its stability when exposed to light and air but can be slightly hygroscopic.

Melting point (Celsius)
288.00
Melting point (Kelvin)
561.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
173.18g/mol
Molar mass
173.1840g/mol
Density
1.4858g/cm3
Appearence

Sulfanilic acid appears as a white to a pale yellow crystalline solid or powder. It can exhibit some degree of hygroscopicity, meaning it can absorb moisture from the air. The crystals are usually quite small and have a distinct grainy texture. This compound is often used in its crystalline form for applications in dye and pigment production.

Comment on solubility

Solubility of 4-acetamidobenzenesulfonic acid

4-acetamidobenzenesulfonic acid, also known as para-aminoacetamidobenzenesulfonic acid, features a complex structure that influences its solubility in various solvents. Its solubility characteristics can be summarized as follows:

  • Water Solubility: This compound is highly soluble in water due to the presence of both a sulfonic acid group and an amide group, which enhance its ability to interact with water molecules through hydrogen bonding.
  • Solvent Polarity: 4-acetamidobenzenesulfonic acid tends to be more soluble in polar solvents compared to nonpolar solvents, aligning with the principle that "like dissolves like."
  • Effect of pH: The solubility can be influenced by pH levels; at lower pH, the sulfonic acid functions better in its protonated form, promoting solubility.
  • Temperature Influence: As with many compounds, increased temperature generally leads to enhanced solubility, allowing for greater solvation of the solute.

Overall, the solubility properties of 4-acetamidobenzenesulfonic acid underline its versatility in both aqueous and organic applications. Its ability to dissolve significantly in water makes it an important compound in various chemical processes. As expressed in solubility terms, "the more functional groups that can interact with the solvent, the more soluble the compound will be."

Interesting facts

Interesting Facts about 4-Acetamidobenzenesulfonic Acid

4-Acetamidobenzenesulfonic acid, often abbreviated as ACBS, is a versatile compound in both organic chemistry and various industrial applications. Here are some engaging insights about this fascinating compound:

  • Structure and Stability: This compound features a unique structure that includes both an acetamide and a sulfonic acid group, giving it its characteristic properties. The combination of these functional groups provides enhanced stability and reactivity.
  • Application in Dyes: ACBS is widely utilized in the dye industry. It serves as an important intermediate in the synthesis of azo dyes, which are known for their vivid colors and are used in textiles and pigments.
  • Biological Relevance: The sulfonic acid group contributes to the compound's solubility in water, making it an interesting subject for biochemistry studies. Its derivatives have shown potential activities as antibacterial agents.
  • Analytical Chemistry: ACBS is also used in analytical chemistry as a reagent for various tests, including the determination of amino acids and other amines. Its ability to form stable complexes makes it a useful tool in quantitative analysis.
  • Chemical Reactivity: Participating in reactions such as sulfonation and acylation, this compound illustrates the principles of reactivity and functional group transformations that are crucial in organic synthesis.
  • Safety Considerations: Like many chemical substances, ACBS must be handled with care. It is essential to follow safety protocols to avoid exposure, ensuring proper lab practices are upheld when working with this compound.

In summary, 4-acetamidobenzenesulfonic acid is not only pivotal in industrial applications but also presents an interesting challenge in research environments, showcasing the beauty and complexity of chemical compounds.

Synonyms
4-acetamidobenzenesulfonic acid
N-Acetylsulfanilic acid
121-62-0
N-Acetylsulphanilic acid
acetanilidsulfonic acid
4-(ACETYLAMINO)BENZENESULFONIC ACID
N-p-acetylanilinosulfonic acid
Benzenesulfonic acid, 4-(acetylamino)-
9B6H3LU885
EINECS 204-487-2
DTXSID0059530
N-ACETYLSULFANILIC ACID [MI]
4-AcetamidobenzenesulfonicAcid-d4(Major)
SULFADIMETHOXINE IMPURITY C [EP IMPURITY]
4-acetamidobenzene-1-sulfonic acid
SULFADIMETHOXINE SODIUM FOR VETERINARY USE IMPURITY C [EP IMPURITY]
SULFADIMETHOXINE IMPURITY C (EP IMPURITY)
UNII-9B6H3LU885
SULFADIMETHOXINE SODIUM FOR VETERINARY USE IMPURITY C (EP IMPURITY)
starbld0018837
CBDivE_002816
CHEMBL131259
SCHEMBL1102016
DTXCID5033676
ZQPVMSLLKQTRMG-UHFFFAOYSA-N
4-Acetylamino-benzenesulfonic acid
AKOS003237084
DB-367266
NS00023970
Q27272299